CSCO Leukemia Young Committee Perspectives | Bringing the Latest AML Advances from EHA 2026 Back to China 

CSCO Leukemia Young Committee Perspectives | Bringing the Latest AML Advances from EHA 2026 Back to China 

The 2026 European Hematology Association (EHA) Congress in Stockholm has concluded, unveiling a series of important advances in acute myeloid leukemia (AML). To help clinicians rapidly interpret the meeting's most impactful findings, the inaugural CSCO Leukemia Young Committee Perspectives webinar was held on June 14 through a collaboration between the CSCO Leukemia Youth Committee and Hematology Frontier. The program was chaired by Professor Qiu Shaowei, Chair of the CSCO Leukemia Committee Youth Group from the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (CAMS). Joining the discussion were Professor Pei Shanzhan from the First Affiliated Hospital, Zhejiang University School of Medicine and Liangzhu Laboratory, Professor Tang Feifei from Peking University People's Hospital, and Professor Cao Yigeng from the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (CAMS). Together, they provided an in-depth review of the latest AML research presented at EHA 2026, highlighting its clinical significance and future implications.
EHA Reflections | Hematology Frontier | Professor Song Qingxiao: Breaking New Ground Through Cellular Metabolism—7-Ketocholesterol Offers a Precision Strategy for Steroid-Refractory Acute GVHD

EHA Reflections | Hematology Frontier | Professor Song Qingxiao: Breaking New Ground Through Cellular Metabolism—7-Ketocholesterol Offers a Precision Strategy for Steroid-Refractory Acute GVHD

Steroid-refractory acute graft-versus-host disease (SR-aGVHD) remains one of the greatest clinical challenges following allogeneic hematopoietic stem cell transplantation (allo-HSCT). At the 2026 European Hematology Association (EHA) Congress, Professor Song Qingxiao from the Second Affiliated Hospital of Army Medical University presented an oral presentation reporting his team's latest discoveries on the pathogenesis of SR-aGVHD. The study demonstrated that 7-ketocholesterol (7-KC) can restore steroid sensitivity by reshaping T-cell lineage metabolism, providing a novel strategy for pre-transplant risk stratification and individualized intervention. During the meeting, Hematology Frontier interviewed Professor Song to discuss the clinical significance of these findings and their potential to overcome one of the most difficult barriers in SR-aGVHD management.
APPLE 2026 | Academician Jia Fan Invites You to APPLE 2026 in Shanghai: Witness China’s Growing Global Leadership in Liver Cancer and Explore AI-Driven Innovation 

APPLE 2026 | Academician Jia Fan Invites You to APPLE 2026 in Shanghai: Witness China’s Growing Global Leadership in Liver Cancer and Explore AI-Driven Innovation 

From July 3–5, 2026, the 16th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2026) will be held in Shanghai. Initiated by the Asia-Pacific Primary Liver Cancer Expert Association (APPLE), supported by the Shanghai Xinxin Medical Technology Development Foundation, and hosted by Zhongshan Hospital, Fudan University, the meeting will focus on the theme "Frontiers in the Diagnosis and Treatment of Primary Liver Cancer in the Era of Artificial Intelligence." Bringing together leading liver cancer experts from the Asia-Pacific region, Europe, and North America, APPLE 2026 will explore emerging strategies for liver cancer prevention and treatment. Following previous editions in 2012 and 2022, this marks the third time APPLE has been hosted in Shanghai, highlighting China's remarkable progress in healthcare, scientific research, and innovation over the past decade. Ahead of the meeting, Oncology Frontier spoke with Congress President Academician Jia Fan of Zhongshan Hospital, Fudan University, who reflected on APPLE's evolution, discussed the changing role of Chinese liver cancer specialists on the global stage, and shared his vision for how artificial intelligence (AI) will transform liver cancer care. Stay tuned for this landmark event.
ASCO 2026 | Prof. Li Mao: Ensartinib’s Global Strategy in the Intensifying ALK+ NSCLC Landscape

ASCO 2026 | Prof. Li Mao: Ensartinib’s Global Strategy in the Intensifying ALK+ NSCLC Landscape

On-site at the 2026 ASCO Annual Meeting, the targeted therapy landscape for ALK-positive non-small cell lung cancer (NSCLC) is witnessing intense competition, with multiple frontline updates from cutting-edge studies reshaping the global dynamics. As a pioneering Chinese homegrown innovative drug making its way onto the world stage, how can ensartinib—Betta Pharmaceuticals' proprietary ALK inhibitor—demonstrate its core value amidst formidable international rivals? MediaMedic had the privilege of an exclusive on-site interview with Professor Li Mao, President of R&D and Chief Medical Officer at Betta Pharmaceuticals, a seasoned leader deeply engaged in precision oncology, to deconstruct ensartinib's distinctive pathway to differentiation and global breakthrough. ADD HASHTAGS
ASCO 2026 | Prof. Kohei Shitara: T-DXd Establishes the New Standard for Second-Line HER2-Positive Advanced Gastric Cancer, with China’s Contributions Driving Global Progress

ASCO 2026 | Prof. Kohei Shitara: T-DXd Establishes the New Standard for Second-Line HER2-Positive Advanced Gastric Cancer, with China’s Contributions Driving Global Progress

The 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, held in Chicago from May 29 to June 2, 2026, showcased several practice-changing advances in oncology. Among the highlights, Prof. Kohei Shitara from the National Cancer Center Hospital East, Japan, presented additional health-related quality of life (HRQoL) data from the landmark DESTINY-Gastric04 trial, further demonstrating the benefits of trastuzumab deruxtecan (T-DXd) in preserving patients' quality of life.
ASCO 2026 | Prof. Xiaotian Zhang and Prof. Yelena Janjigian: The DESTINY-Gastric Program Reshapes HER2-Targeted Therapy in Gastric Cancer as Chinese and U.S. Experts Discuss the Next Chapter

ASCO 2026 | Prof. Xiaotian Zhang and Prof. Yelena Janjigian: The DESTINY-Gastric Program Reshapes HER2-Targeted Therapy in Gastric Cancer as Chinese and U.S. Experts Discuss the Next Chapter

The landmark results of the DESTINY-Gastric04 (DG04) trial have firmly established trastuzumab deruxtecan (T-DXd) as the missing piece in second-line HER2-targeted treatment for gastric cancer. At the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, the DESTINY-Gastric03 (DG03) study was also unveiled, highlighting the promising potential of T-DXd in the first-line setting. As T-DXd moves from later-line therapy toward frontline treatment for HER2-positive gastric cancer, an increasing number of patients stand to benefit.
Precise Characterization of Transplant Prognosis: From DTA Mutation Monitoring to TP53 Aberration Stratification, Experts at EHA 2026 Discuss Changing Landscape of Myeloid Neoplasm Treatment 

Precise Characterization of Transplant Prognosis: From DTA Mutation Monitoring to TP53 Aberration Stratification, Experts at EHA 2026 Discuss Changing Landscape of Myeloid Neoplasm Treatment 

The 2026 European Hematology Association (EHA) Annual Meeting was grandly held in Madrid, Spain. As one of the most influential academic events in the global hematology field, the application of allo-HSCT in myeloid neoplasms remains a focus of academic debate and innovation. This specialized session, chaired by Professor Anna Sureda (Catalan Institute of Oncology, Barcelona, Spain), focused on post-transplant molecular monitoring, refinement of prognostic strategies, and algorithm optimization for refractory cases in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Research teams from China, Switzerland, Sweden, Spain, and other countries shared five milestone academic reports, providing new evidence-based medical grounds for clinical precision transplantation.
EHA 2026 Authoritative Release: Major Update of CLL and Richter Transformation Guidelines, Opening a New Era of Precision and Fixed-Duration Therapy 

EHA 2026 Authoritative Release: Major Update of CLL and Richter Transformation Guidelines, Opening a New Era of Precision and Fixed-Duration Therapy 

At the 2026 European Hematology Association (EHA) Annual Meeting, experts including Professor Paolo Ghia from Università Vita-Salute San Raffaele, Professor Barbara Eichhorst from the University Hospital of Cologne, and Professor Elżbieta Kalicińska from Wroclaw Medical University jointly released and interpreted the latest version of the "EHA Guidelines for the Management of Chronic Lymphocytic Leukemia (CLL) and Richter Transformation (RT)". This update not only incorporates data from multiple cutting-edge targeted studies but also includes "Richter Transformation" in the title for the first time, aiming to provide a more practical clinical pathway for hematologists worldwide.
Breaking the Stalemate in CALR-Mutated Myelofibrosis: INCA033989 Demonstrates Deep Disease-Modifying Potential and Bone Marrow Morphological Improvement 

Breaking the Stalemate in CALR-Mutated Myelofibrosis: INCA033989 Demonstrates Deep Disease-Modifying Potential and Bone Marrow Morphological Improvement 

At the 2026 European Hematology Association (EHA) Annual Congress, Professor Claire Harrison from Guy's and St Thomas' NHS Foundation Trust, London, shared the latest research data on the mutation-specific monoclonal antibody INCA033989 (hereinafter referred to as "989") for the treatment of calreticulin (CALR)-mutated myelofibrosis (MF) patients. This study aims to evaluate the safety, tolerability, and preliminary efficacy of this first-in-class drug in monotherapy and combination regimens, providing a new path for precision treatment in this specific subpopulation of CALR-mutated patients.
Targeting the 8 kPa Prognostic Threshold: EBMT-EHA Thalassemia Gene Therapy Guideline Update Strengthens Precise Liver Risk Assessment 

Targeting the 8 kPa Prognostic Threshold: EBMT-EHA Thalassemia Gene Therapy Guideline Update Strengthens Precise Liver Risk Assessment 

At the 2026 European Hematology Association (EHA) Annual Meeting, Professor Giuseppe De Franceschi from the University of Verona, Italy, representing the joint working group of the European Society for Blood and Marrow Transplantation (EBMT) and EHA, delivered an in-depth interpretation of the latest update to the "Guidelines for Patient Selection for Gene Therapy in Transfusion-Dependent β-Thalassemia (TDT)." This guideline update aims to integrate the latest clinical evidence from gene addition and gene editing technologies to provide standardized patient screening and follow-up pathways for hematologists worldwide.