UroStream

From June 11–14, 2026, the 2026 Annual Meeting of the Chinese Urological Association of the Chinese Medical Doctor Association (CUDA) was held in Zhengzhou, Henan Province. The meeting was hosted by the Chinese Medical Doctor Association (CMDA) and the Chinese Urological Association of the CMDA (CUDA), and jointly organized by The First Affiliated Hospital of Zhengzhou University, Henan Provincial People's Hospital, and The First Affiliated Hospital of Henan University, with additional support from Henan Cancer Hospital, The First Affiliated Hospital of Henan University of Chinese Medicine, and The Second Affiliated Hospital of Zhengzhou University.

Hosted by the Chinese Medical Doctor Association (CMDA) and the Chinese Urological Association of the CMDA (CUDA), the 2026 CUDA Annual Meeting was held in Zhengzhou, Henan Province, from June 11–14, 2026. The meeting was jointly organized by The First Affiliated Hospital of Zhengzhou University, Henan Provincial People's Hospital, and The First Affiliated Hospital of Henan University, with additional support from Henan Cancer Hospital, The First Affiliated Hospital of Henan University of Chinese Medicine, and The Second Affiliated Hospital of Zhengzhou University.

Hosted by the Chinese Medical Doctor Association (CMDA) and the Chinese Urological Association of the CMDA (CUDA), the 2026 CUDA Annual Meeting was held in Zhengzhou, Henan Province, from June 11–14, 2026. Continuing the discipline's mission of "Healthy China, Urology at the Forefront," this year's conference was themed "Collaboration and Innovation for Future Development." The scientific program featured in-depth discussions on precision surgery, advances in minimally invasive techniques, and the evolving role of robotic surgery through expert lectures, live surgical demonstrations, and multidisciplinary forums.

With the rapid evolution of antibody-drug conjugates (ADCs) and immunotherapy, the treatment paradigm for urothelial carcinoma (UC) is undergoing profound transformation. During the recent China Clinical Oncology Annual Advances Symposium (BOC) and Best of CSCO 2026 China, leading oncology experts gathered to discuss the latest international advances and their translation into clinical practice.

In recent years, the treatment landscape for urothelial carcinoma (UC) has entered the era of precision medicine, with emerging therapeutic strategies offering new hope for patients. At the recent China Clinical Oncology Annual Advances Symposium (BOC) and Best of CSCO 2026 China, experts highlighted China's most significant original oncology achievements of the year and reviewed major advances in precision oncology across multiple tumor types, including genitourinary cancers, further advancing standardized cancer care in China.

As the prevalence of kidney stones continues to rise and complex stone disease becomes increasingly common, there is growing demand for minimally invasive, effective, and safe treatment strategies. Flexible ureteroscopy has become a cornerstone of upper urinary tract stone management; however, its role in treating large stone burdens, infection-related stones, and anatomically complex cases remains a subject of debate. Meanwhile, advances such as laser lithotripsy, single-use ureteroscopes, and suction-assisted access sheaths continue to expand treatment possibilities. Balancing maximal stone clearance with minimal complications remains one of the key challenges in modern endourology.

Transurethral resection of bladder tumor (TURBT) remains the standard treatment for non-muscle-invasive bladder cancer (NMIBC). However, up to 45% of patients experience tumor recurrence within one year following TURBT alone. Although intravesical therapies—including cytotoxic agents and immunotherapy—are widely used, substantial unmet clinical needs remain, underscoring the need for more effective treatment strategies.

The 2026 American Society of Clinical Oncology (ASCO) Annual Meeting once again brought together the latest advances in cancer research from around the world. Among the most closely watched areas was radioligand therapy (RLT) for prostate cancer. During the meeting, the ProstACT Global 3 study team presented the first Part 1 results from its Phase III trial, focusing on the safety and dosimetry of TLX591 (¹⁷⁷Lu-rosopatamab tetraxetan). These findings provide early evidence supporting the feasibility of integrating TLX591 with standard-of-care treatment for patients with metastatic castration-resistant prostate cancer (mCRPC), while also demonstrating encouraging preliminary efficacy signals.

During the 2nd Peking University Urology Forum and the celebration of the 80th anniversary of the Department of Urology at Peking University First Hospital, Oncology Frontier – UroStream interviewed Prof. Weiren Huang from the Department of Urology, First Affiliated Hospital of Shenzhen University (Shenzhen Second People’s Hospital).

Chinese-developed immune checkpoint inhibitors, represented by toripalimab, are accelerating the transition of innovative therapies in urologic oncology from followers to global contributors. At the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, Chinese innovation was not only featured in oral presentations but also prominently showcased in the poster halls. Toripalimab combined with 9MW2821 demonstrated promising bladder-preservation potential after moving from advanced disease into the perioperative setting. Immunotherapy plus chemotherapy expanded a uniquely Chinese approach to bladder preservation. Meanwhile, a phase III neoadjuvant trial of toripalimab combined with axitinib in renal cell carcinoma marked the first randomized evaluation of a targeted-immunotherapy combination moving from the frontline setting into neoadjuvant treatment. In this issue, Oncology Frontier invited Professor Yijun Shen from Fudan University Shanghai Cancer Center to discuss key poster presentations and share his perspectives on the evolving landscape of immunotherapy in urologic oncology at this year's ASCO meeting.