Digital Management of Chronic Progressive Liver Disease in China: Monthly Literature Review (April 2024, Issue 80)

Digital Management of Chronic Progressive Liver Disease in China: Monthly Literature Review (April 2024, Issue 80)

Hello, esteemed experts and colleagues. In this issue of the CDM Monthly Review (Issue 80), we will share six recent articles on the diagnosis and treatment of portal hypertension (four on diagnosis and monitoring, and two on multidisciplinary treatment). We have invited the following experts to review this month's issue: Dr. Yifei Huang from the Department of Gastroenterology at the Third Affiliated Hospital,Sun Yat-sen University, Professor Yali Xiong from the Department of Infectious Diseases at Nanjing Drum Tower Hospital, and Dr. Jiacheng Liu from the Department of Interventional Radiology at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology.
Professor Shichun Lu’s Team: Proportion of Viable Tumor Cells Predicts Prognosis of Targeted Immunotherapy for Liver Cancer

Professor Shichun Lu’s Team: Proportion of Viable Tumor Cells Predicts Prognosis of Targeted Immunotherapy for Liver Cancer

Recently, Professor Shichun Lu's team from the Chinese PLA General Hospital published an article titled "Application of Proportion of Viable Tumor Cells in Prognosis Evaluation of Initial Unresectable Hepatocellular Carcinoma Patients Undergoing Sequential Surgical Treatment After Conversion Therapy" in the professional journal Chinese Journal of Hepatobiliary Surgery. The study retrospectively analyzed clinical data and pathological evaluations of 80 initially unresectable HCC patients who received PD-1 antibody combined with tyrosine kinase inhibitors (TKIs) as conversion therapy followed by sequential surgical treatment. The research team confirmed the value of the proportion of viable tumor cells (RVTCs) in surgical pathology specimens as a prognostic marker for patients undergoing conversion surgery and identified the optimal threshold for RVTCs (15%) and factors influencing achieving RVTCs ≤ 15% postoperatively.
EBMT China’s Voice | Team led by Yi Luo/Yibo Wu: Current Treatment Status and Prognosis of Acute Myeloid Leukemia with t(8;21) Chromosome Translocat

EBMT China’s Voice | Team led by Yi Luo/Yibo Wu: Current Treatment Status and Prognosis of Acute Myeloid Leukemia with t(8;21) Chromosome Translocat

Acute myeloid leukemia (AML) with t(8;21)(q22;q22.1) is one subtype among AML with recurrent genetic abnormalities, characterized by the translocation between chromosome 8q22 and chromosome 21q22. This translocation leads to the fusion of the RUNX1 gene on 8q22 with the RUNX1T1 gene on 21q22, forming the RUNX1-RUNX1T1 fusion gene. From April 14th to 17th, 2024, the 50th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) was held in Glasgow, UK. The conference focused on the latest advancements in stem cell transplantation and cell therapy, advancing towards better clinical outcomes for patients with hematologic diseases and blood tumors. In this congress, the team led by Yi Luo/Yibo Wu from The First Affiliated Hospital of Zhejiang University School of Medicine in China presented a clinical study, sharing the treatment status and prognosis of AML with t(8;21)(q22;q22.1). This journal is honored to invite Dr. Yibo Wu to share the research findings and their clinical significance with colleagues.
Professor Jun Guo Interprets the Updated CSCO Guidelines on Urothelial Carcinoma and Melanoma | 2024 CSCO Guideline Conference

Professor Jun Guo Interprets the Updated CSCO Guidelines on Urothelial Carcinoma and Melanoma | 2024 CSCO Guideline Conference

The 2024 CSCO Guideline Conference, co-hosted by the Chinese Society of Clinical Oncology (CSCO) and the Beijing Hope Science Clinical Oncology Research Foundation, took place in Jinan on April 26-27. At the event, Professor Jun Guo from Peking University Cancer Hospital was interviewed by "Oncology Frontier." He discussed significant updates in the new editions of the CSCO guidelines for urothelial carcinoma and melanoma, shared insights into the unique features of the CSCO guidelines, and provided an overview of the current and future states of anti-cancer drug development in China.
Professor Rui Ge: Review and Outlook on Advances in Breast Cancer Treatment | Northern Breast Cancer Salon Annual Review

Professor Rui Ge: Review and Outlook on Advances in Breast Cancer Treatment | Northern Breast Cancer Salon Annual Review

As time passes and seasons flow, we always embark on new journeys and endeavors through repeated reviews and outlooks. The annual review of the Northern Breast Cancer Salon and the discussion on the 2024 CSCO BC Guidelines update were held from January 5-6, 2024, in Beijing. "Oncology Frontier" specially interviewed Professor Rui Ge from East Hospital affiliated with Fudan University to reflect on the progress in breast cancer treatment i
Professor Ying Yuan: Updates to the 2024 CSCO Guidelines for Colorectal Cancer – Enhancing Personalized Treatment from Pathology to Therapy

Professor Ying Yuan: Updates to the 2024 CSCO Guidelines for Colorectal Cancer – Enhancing Personalized Treatment from Pathology to Therapy

The 2024 update of the Chinese Society of Clinical Oncology (CSCO) Guidelines for the Diagnosis and Treatment of Colorectal Cancer has been released. The new edition incorporates the latest evidence-based medical developments, adds new biomarkers for colorectal cancer, enriches clinical treatment strategy options, and adjusts the recommendation levels for various treatment protocols. Oncology Frontier interviewed Professor Ying Yuan from The Second Affiliated Hospital of Zhejiang University School of Medicine, one of the guideline's authors, to discuss the key updates and their clinical significance.
EAU24 Expert Commentary | Professor Fufu Zheng: NMIBC Postoperative Intravesical Therapy Strategies and Research Progress

EAU24 Expert Commentary | Professor Fufu Zheng: NMIBC Postoperative Intravesical Therapy Strategies and Research Progress

Transurethral resection of bladder tumor (TURBt) is the primary treatment for non-muscle-invasive bladder cancer (NMIBC), but the postoperative tumor recurrence rate remains high, posing a significant clinical challenge. To prevent tumor recurrence, different intravesical therapies are administered post-TURBt based on the patient's recurrence risk level. At the 2024 39th Annual European Association of Urology (EAU24) Congress, several studies focused on postoperative intravesical therapy strategies for NMIBC. Professor Fufu Zheng from The First Affiliated Hospital of Sun Yat-sen University provided a detailed analysis of these studies, exploring precise and individualized treatment strategies for NMIBC.
Hepatol Int丨Long-term Prognosis of Robotic Liver Resection for Hepatocellular Carcinoma is Safe and Effective

Hepatol Int丨Long-term Prognosis of Robotic Liver Resection for Hepatocellular Carcinoma is Safe and Effective

Primary liver cancer (PLC) is one of the most common cancers worldwide and a leading cause of cancer-related deaths, with hepatocellular carcinoma (HCC) accounting for about 85% of all PLC cases. Despite continuous advancements in medical technology, radical surgical resection of the primary tumor remains a key component of HCC treatment. Robotic liver resection (RLR) is a relatively new technique that combines the advantages of traditional surgery with the precision and flexibility of robotic surgical systems. However, it remains unclear whether RLR is superior to traditional surgery in clinical practice.
Professor Jun Zhu: Rapid Advances in Clinical Trials Usher in a New Era for Lymphoma Diagnosis and Treatment! | 2024 Nanjing Lymphoma Forum

Professor Jun Zhu: Rapid Advances in Clinical Trials Usher in a New Era for Lymphoma Diagnosis and Treatment! | 2024 Nanjing Lymphoma Forum

Amidst the gentle breeze of early summer, the annual "Nanjing Lymphoma Forum" was grandly held in the historic city of Nanjing. This offline event gathered renowned experts in the field of lymphoma from both domestic and international spheres. Through lectures, case discussions, and other formats, the forum facilitated exchanges on the latest achievements and developments in basic and clinical lymphoma research. "Oncology frontier- Hematology frontier" had the privilege of interviewing Professor Jun Zhu, one of the conference chairs and a prominent figure from Peking University Cancer Hospital. He shared the latest research on new drugs such as antibody-drug conjugates (ADCs), bispecific antibodies, and Bruton tyrosine kinase (BTK) inhibitors, emphasizing the crucial role of clinical trials in lymphoma treatment.
EAU24 On-Site Highlights | Professor Wei Zhai: Advances in Urological Tumor Research to Improve Patient Prognosis

EAU24 On-Site Highlights | Professor Wei Zhai: Advances in Urological Tumor Research to Improve Patient Prognosis

The 39th Annual European Association of Urology (EAU24) Congress took place from April 5-8, 2024, in Paris, France, focusing on global urological oncology hotspots and the forefront of Chinese urological research. At the event, "Oncology Frontier" invited Professor Wei Zhai from Renji Hospital, affiliated with Shanghai Jiao Tong University School o,(f Medicine, to share his insights and the latest developments in urological oncology research.