APPLE 2026 | Prof. Masatoshi Kudo: Reconstructing Systemic-Locoregional Therapeutic Strategies for Hepatocellular Carcinoma in the Immuno-Oncology Era 

APPLE 2026 | Prof. Masatoshi Kudo: Reconstructing Systemic-Locoregional Therapeutic Strategies for Hepatocellular Carcinoma in the Immuno-Oncology Era 

As hepatocellular carcinoma (HCC) treatment enters the wave of immuno-oncology (IO) combinations, the paradigm of combining systemic therapy with locoregional treatments (LRT) is undergoing a qualitative leap—evolving from incremental gains to a fundamental reconstruction. Held from July 3–5, 2026, the 16th Asia-Pacific Primary Liver Cancer Expert (APPLE) Meeting convened in Shanghai, bringing together leading experts from across the Asia-Pacific, Europe, and North America to discuss novel strategies for liver cancer prevention and management.
World Hepatitis Day 2025 | Prof. George Lau: Exploring Optimal Strategies for HBV Antiviral Therapy from an Economic Perspective

World Hepatitis Day 2025 | Prof. George Lau: Exploring Optimal Strategies for HBV Antiviral Therapy from an Economic Perspective

At the 2025 World Hepatitis Day Campaign Conference and the 7th Academic Conference on Clinical Cure of Chronic Hepatitis B, hosted by the China Foundation for Hepatitis Prevention and Control, Professor George Lau, Chairman of Hong Kong’s Humanity Medical Group and Chief Physician at Zhongshan Hospital affiliated with Fudan University, shared insights on the most cost-effective strategies for HBV antiviral therapy from an economic perspective. Hepatology Digest invited Prof. George Lau for an in-depth interview on the current status of hepatitis B prevention and treatment as well as economic evaluation.
APASL 2025 Expert Interview | Prof. George Lau: Dilemmas and Breakthroughs in Clinical Cure of Chronic Hepatitis B and Liver Cancer Prevention

APASL 2025 Expert Interview | Prof. George Lau: Dilemmas and Breakthroughs in Clinical Cure of Chronic Hepatitis B and Liver Cancer Prevention

At the 34th Annual Meeting of the Asian Pacific Association for the Study of the Liver (APASL 2025), Professor George Lau, Chairman of Hong Kong Humanity Medical Group and Director of Humanity Medical Clinical Research Center, shared important insights on cuttingedge topics including clinical cure of chronic hepatitis B (CHB) and liver cancer prevention. With the WHO’s 2030 goal to eliminate CHB approaching, China’s CHB prevention and treatment efforts face new opportunities and challenges. In this exclusive interview, drawing on his extensive clinical experience, Professor Lau systematically outlines key breakthroughs and remaining dilemmas in the fields of CHB clinical cure and liver cancer prevention, offering valuable professional perspectives to advance China’s work in CHB and liver cancer control.
Any level of alcohol can be harmful for MASLD patients

Any level of alcohol can be harmful for MASLD patients

A recent study by Prof. Wai-Kay Seto (The University of Hong Kong) and Prof. Jie Li (Drum Tower Hospital, Nanjing University Medical School), published in Alimentary Pharmacology & Therapeutics, systematically reviewed the epidemiology, pathogenic mechanisms, and prognostic impact of alcohol use in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), showing that alcohol consumption significantly complicates disease progression and prognosis.