Professor Yu Wang: Innovations and Advances in Transplantation Strategies for AML
Acute myeloid leukemia (AML) is a heterogeneous group of malignant clonal disorders originating from myeloid stem cells, characterized by significant biological diversity and generally poor prognosis. The global disease burden of AML continues to rise, with the age-standardized incidence increasing by 87.3% between 1990 and 2021, underscoring the urgent need for improved therapeutic strategies.
Annual Meeting of the Hematology Branch of CPAM 2026 | Professor Sanbin Wang: Interpreting the DSA Consensus and Clinical Strategies
From April 10 to 11, 2026, the Annual Academic Meeting of the Hematology Branch of the China International Exchange and Promotive Association for Medical and Health Care (CPAM), together with the “Huatuo Project” MDT Workshop, was held in Changsha.
North–South Summit 2026 | Professor Jia Wang: In the Era of Neoadjuvant Immunotherapy for Triple-Negative Breast Cancer—Is Platinum Still Essential?
In the era of neoadjuvant immunotherapy for triple-negative breast cancer (TNBC), an important clinical question has emerged: is platinum still indispensable? During the “Deep Dive” session at the 8th North–South Breast Cancer Forum, Professor Jia Wang from Zhongshan Hospital, Dalian University presented an in-depth analysis of this issue. Drawing on treatment goals, mechanistic rationale, clinical evidence, and individualized strategies, she systematically reviewed the role and challenges of platinum agents in neoadjuvant immunotherapy for TNBC and proposed future directions toward precision “de-escalation” therapy.
Annals of Oncology: Academician Binghe Xu and Professor Tao Sun Report the OPTIMAL Study—Oral Paclitaxel Demonstrates Non-Inferiority to Intravenous Therapy in HER2-Negative Advanced Breast Cancer
On March 14, 2026, the international oncology journal Annals of Oncology (2025 IF: 65.4), the official journal of the European Society for Medical Oncology (ESMO), published the results of the international multicenter phase III OPTIMAL trial (NCT03315364). The study was led by Academician Binghe Xu (first author) from the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences, and Professor S-B. Kim (corresponding author), with key contributions from Professor Tao Sun (Liaoning Cancer Hospital) and Professor H. Jeong (Asan Medical Center, University of Ulsan College of Medicine), among other international collaborators. For the first time, the study demonstrated that oral paclitaxel (DHP107) is non-inferior to weekly intravenous paclitaxel in first-line treatment of HER2-negative recurrent or metastatic breast cancer, with lower neurotoxicity and greater convenience—offering patients a safer and more accessible therapeutic option.
Breaking Mechanistic Barriers, Advancing Therapeutics — Professor Zeping Zhou on New Developments and Long-Term Management Strategies in ITP
Immune thrombocytopenia (ITP) is a complex autoimmune disorder involving multiple immune pathways and abnormalities in platelet production. In recent years, continuous advances in drug development and evolving treatment paradigms have been reshaping the clinical landscape of ITP.
Deciphering VEXAS Syndrome: From UBA1 Somatic Mutations to Precision Management and Allo-HSCT
During the recent workshop "Focus on Allogeneic HSCT in Myelodysplastic Syndromes," Professor Fabio Ciceri (IRCCS San Raffaele Scientific Institute / Vita-Salute San Raffaele University), Chair of the EBMT Scientific Council and the Acute Leukemia Working Party (ALWP), provided a comprehensive overview of "Contemporary Approaches to VEXAS." He systematically detailed the genetic foundations, clinical progression, and multidimensional therapeutic landscape of this complex disease.
Professor Ming Hou: From “Following” to “Leading”—Key Updates in the 2025 Chinese Guidelines for Adult Immune Thrombocytopenia
In March, as spring brings renewed vitality to Beijing, the 9th Beijing Conference on Thrombosis and Hemostasis, together with the 7th Beijing Hematologic Oncology and Immunology Summit Forum, was held from March 27 to 28, 2026. Centered on advances in the diagnosis and treatment of thrombotic and hemostatic disorders, as well as hematologic malignancies and immunology, the meeting highlighted cutting-edge developments and evolving clinical strategies.
EAU26 Afternoon Dialogue | Xuesong Li: ADC Plus Radiotherapy in the Perioperative Setting Breaks Therapeutic Barriers and Opens a New Era of Precision Treatment for UTUC
At the 2026 European Association of Urology Congress (EAU26), held in London, major advances in urologic oncology were presented. Among them, the work of Professor Xuesong Li’s team from Peking University First Hospital attracted considerable attention. The team not only contributed important achievements in upper urinary tract reconstruction but also presented a phase II clinical study of disitamab vedotin combined with radiotherapy for upper tract urothelial carcinoma (UTUC), offering a promising new treatment option.
EBMT 2026 China Voice | Professor Xing-Yu Cao: Sequential CD7 CAR-T Followed by Second Transplant Improves Survival to Nearly 50% in Post-Transplant Relapsed T-ALL/LBL
Patients with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) who relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) have an extremely poor prognosis. Historically, treatment options have been limited, and even with a second transplant, long-term survival has remained below 30%. There is therefore an urgent need for more effective therapeutic strategies.