ASCO China Voice | Professor Hui Xie: BMI May Serve as a Simple Stratification Marker for Trastuzumab Deruxtecan in Advanced Breast Cancer

ASCO China Voice | Professor Hui Xie: BMI May Serve as a Simple Stratification Marker for Trastuzumab Deruxtecan in Advanced Breast Cancer

At the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, a study led by Professor Hui Xie from Jiangsu Cancer Hospital was presented as an electronic poster (Abstract e13078). Using multicenter real-world data from China, the study is the first to systematically evaluate the relationship between body mass index (BMI) and the efficacy and safety of trastuzumab deruxtecan (T-DXd) in patients with HER2-positive or HER2-low advanced breast cancer.
CSCO Leukemia Young Committee Perspectives | Bringing the Latest AML Advances from EHA 2026 Back to China 

CSCO Leukemia Young Committee Perspectives | Bringing the Latest AML Advances from EHA 2026 Back to China 

The 2026 European Hematology Association (EHA) Congress in Stockholm has concluded, unveiling a series of important advances in acute myeloid leukemia (AML). To help clinicians rapidly interpret the meeting's most impactful findings, the inaugural CSCO Leukemia Young Committee Perspectives webinar was held on June 14 through a collaboration between the CSCO Leukemia Youth Committee and Hematology Frontier. The program was chaired by Professor Qiu Shaowei, Chair of the CSCO Leukemia Committee Youth Group from the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (CAMS). Joining the discussion were Professor Pei Shanzhan from the First Affiliated Hospital, Zhejiang University School of Medicine and Liangzhu Laboratory, Professor Tang Feifei from Peking University People's Hospital, and Professor Cao Yigeng from the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (CAMS). Together, they provided an in-depth review of the latest AML research presented at EHA 2026, highlighting its clinical significance and future implications.
Precise Characterization of Transplant Prognosis: From DTA Mutation Monitoring to TP53 Aberration Stratification, Experts at EHA 2026 Discuss Changing Landscape of Myeloid Neoplasm Treatment 

Precise Characterization of Transplant Prognosis: From DTA Mutation Monitoring to TP53 Aberration Stratification, Experts at EHA 2026 Discuss Changing Landscape of Myeloid Neoplasm Treatment 

The 2026 European Hematology Association (EHA) Annual Meeting was grandly held in Madrid, Spain. As one of the most influential academic events in the global hematology field, the application of allo-HSCT in myeloid neoplasms remains a focus of academic debate and innovation. This specialized session, chaired by Professor Anna Sureda (Catalan Institute of Oncology, Barcelona, Spain), focused on post-transplant molecular monitoring, refinement of prognostic strategies, and algorithm optimization for refractory cases in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Research teams from China, Switzerland, Sweden, Spain, and other countries shared five milestone academic reports, providing new evidence-based medical grounds for clinical precision transplantation.
ASCO China Voice | Prof. Junxing Chen: PUNCH03 Demonstrates Early Promise as Disitamab Vedotin Plus BCG Offers a New Chinese Strategy for High-Risk NMIBC 

ASCO China Voice | Prof. Junxing Chen: PUNCH03 Demonstrates Early Promise as Disitamab Vedotin Plus BCG Offers a New Chinese Strategy for High-Risk NMIBC 

Transurethral resection of bladder tumor (TURBT) remains the standard treatment for non-muscle-invasive bladder cancer (NMIBC). However, up to 45% of patients experience tumor recurrence within one year following TURBT alone. Although intravesical therapies—including cytotoxic agents and immunotherapy—are widely used, substantial unmet clinical needs remain, underscoring the need for more effective treatment strategies.
Breaking the MM Treatment Burden: Precision Prevention of Infection, Optimization of Administration Routes, and Future Outlook for Trispecific Antibodies 

Breaking the MM Treatment Burden: Precision Prevention of Infection, Optimization of Administration Routes, and Future Outlook for Trispecific Antibodies 

At the 2026 European Hematology Association (EHA) Annual Meeting, managing the treatment burden of multiple myeloma (MM) became a core topic. As innovative therapies such as bispecific antibodies (BsAbs) and CAR-T enter clinical practice, how to reduce patient infection risks, optimize the convenience of administration, and improve quality of life while pursuing deep remission has become a major challenge for clinicians. This meeting invited Professor Joseph Mikhael from City of Hope, Professor Maria-Victoria Mateos from the University Hospital of Salamanca, and Professor Xavier Leleu from Poitiers University Hospital to conduct an in-depth discussion on "Managing the Burden of MM Treatments."
Moving from Relapsed/Refractory to Early Treatment: Professor Cyrille Touzeau Interprets the EMN34 Study, Elranatamab Opens a New Chapter in Precision Intervention for HR SMM

Moving from Relapsed/Refractory to Early Treatment: Professor Cyrille Touzeau Interprets the EMN34 Study, Elranatamab Opens a New Chapter in Precision Intervention for HR SMM

In the evolution of treatment for Multiple Myeloma (MM), moving highly effective therapies forward to the early stages of the disease has become a current research hotspot. For patients with High-Risk Smoldering Multiple Myeloma (HR SMM), whether early active intervention can delay or even prevent its transformation into active myeloma is a focus of clinical attention. At a recent international academic conference, Professor Cyrille Touzeau from the University Hospital of Nantes in France shared the preliminary results of the ERASMM (EMN34) study. This study aimed to evaluate the safety and efficacy of the BCMA×CD3 bispecific antibody Elranatamab in patients with HR SMM. This journal has specially compiled the highlights of the conference for our readers.
100% Objective Response Rate! AMC-095 Study Confirms the Efficacy and Safety of Ibrutinib Integrated into R-da-EPOCH for HIV-Associated DLBCL

100% Objective Response Rate! AMC-095 Study Confirms the Efficacy and Safety of Ibrutinib Integrated into R-da-EPOCH for HIV-Associated DLBCL

At the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, Professor Ida Wong-Sefidan (MD) from the AIDS Malignancy Consortium (AMC), on behalf of the research team, shared a milestone study. This study aimed to evaluate the clinical benefits of the Bruton's tyrosine kinase (BTK) inhibitor Ibrutinib in combination with dose-adjusted R-EPOCH (R-da-EPOCH) for the treatment of Human Immunodeficiency Virus-associated Diffuse Large B-cell Lymphoma (HIV-DLBCL). The study results not only confirmed the safety of the regimen but also provided critical data support in terms of efficacy and subgroup survival analysis.
ASCO Voices from China | Zhihui Li: Large Real-World Study Highlights the Value of CAR-T-to-Transplant Consolidation in R/R B-ALL

ASCO Voices from China | Zhihui Li: Large Real-World Study Highlights the Value of CAR-T-to-Transplant Consolidation in R/R B-ALL

The treatment of relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) remains a major clinical challenge. While CAR-T cell therapy can induce rapid and deep remissions, many patients continue to face a substantial risk of relapse. Consolidation with allogeneic hematopoietic stem cell transplantation (allo-HSCT) following CAR-T therapy has emerged as a promising curative strategy. However, evidence regarding its long-term efficacy, optimal timing, and the role of molecular biomarkers in guiding treatment decisions has remained limited.