Informations

In the evolution of treatment for Multiple Myeloma (MM), moving highly effective therapies forward to the early stages of the disease has become a current research hotspot. For patients with High-Risk Smoldering Multiple Myeloma (HR SMM), whether early active intervention can delay or even prevent its transformation into active myeloma is a focus of clinical…

In the field of relapsed/refractory classical Hodgkin lymphoma (R/R cHL), although the application of immune checkpoint inhibitors (such as anti-PD-1) and antibody-drug conjugates (such as Brentuximab Vedotin, BV) has significantly improved patient prognosis, clinical challenges remain severe for patients who fail multiple lines of therapy. Recently, at an international academic conference, Professor Enrico Derenzini, on…

At a recent international oncology symposium, Professor François-Clément Bidard from Institut Curie shared the updated results from the third data cut-off (DCO3) of the Phase III SERENA-6 study. The study focuses on patients with HR+/HER2- advanced breast cancer (ABC). During first-line treatment with an aromatase inhibitor (AI) combined with a CDK4/6 inhibitor (CDK4/6i), once a…

Diffuse Large B-Cell Lymphoma (DLBCL) is the most common subtype of Non-Hodgkin Lymphoma (NHL). Although the R-CHOP regimen has established its position as the cornerstone of first-line treatment, approximately 40% of high-risk patients still face the dilemma of refractory or relapsed disease. At a recent academic conference, Professor Georg Lenz from University Hospital Münster, Germany,…

At the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, Professor Ida Wong-Sefidan (MD) from the AIDS Malignancy Consortium (AMC), on behalf of the research team, shared a milestone study. This study aimed to evaluate the clinical benefits of the Bruton’s tyrosine kinase (BTK) inhibitor Ibrutinib in combination with dose-adjusted R-EPOCH (R-da-EPOCH) for the…

In the field of surgical treatment for breast cancer, the trend of “de-escalation” in axillary management has become a consensus. Although studies such as ACOSOG Z011 and AMAROS have laid the foundation for exempting axillary lymph node dissection (ALND) in patients with positive sentinel lymph nodes (SLN), controversy remains in clinical practice regarding whether it…

At a recent international breast cancer academic conference, Professor Nicholas C. Turner from The Royal Marsden Hospital and the Institute of Cancer Research (ICR) in the UK presented the highly anticipated primary analysis results of the Phase III persevERA BC study. This study aimed to evaluate the efficacy and safety of a novel oral selective…