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Annual Meeting of the Hematology Branch of the China International Exchange and Promotive Association for Medical and Health Care
Thrombotic diseases are associated with high incidence, mortality, and disability rates, posing a serious threat to public health. Venous thromboembolism (VTE), in particular, often presents insidiously, and dislodged thrombi can lead to pulmonary embolism—earning it the reputation of a “silent killer.”
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Expert Interview | Prof. Shilpa Gupta Decodes Urothelial Carcinoma In-Depth: China’s Strength, Global Collaboration and Future Breakthroughs in the ADC Era
In recent years, the rapid advancement of antibody-drug conjugates (ADCs) has completely reshaped the treatment paradigm across the entire disease course of urothelial carcinoma. Meanwhile, Chinese investigators and domestically developed innovative agents have gained ever-increasing influence in the global oncology landscape. Recently, we had the exclusive opportunity to interview Prof. Shilpa Gupta, a world-leading expert…
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Overcoming Antigen Escape: CD19/CD84 “If-Better” Dual CAR-T Cells Demonstrate Superior Control in CD19-Low B-ALL
At the recent EBMT 2026 Annual Meeting, Prof. Ane Altuna Mongelos from Hospital Clínic de Barcelona and IDIBAPS delivered a presentation titled “CD19/CD84 IF-BETTER dual CAR T cells demonstrate superior control of CD19-low B-ALL than single CAR19.” The report explored novel pathways to overcome antigen escape in B-cell acute lymphoblastic leukemia (B-ALL) through a dual-targeting…
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Overcoming Delayed Engraftment: UM171 Expansion Technology and ATG-free Regimens Reshape the CBT Landscape
As the landscape of hematopoietic stem cell transplantation (HSCT) continues to evolve, umbilical cord blood transplantation (CBT) maintains a critical position in the treatment of hematologic malignancies due to its unique immunological advantages. However, delayed engraftment and high non-relapse mortality (NRM) were once significant bottlenecks limiting its clinical utility. At a recent academic symposium, Professor…
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Breaking the Bottleneck in Severe Aplastic Anemia: Insights from EBMT Registry Big Data, Long-term IST Follow-up, and Novel Biological Predictors
Severe Aplastic Anemia (SAA), as a highly heterogeneous bone marrow failure (BMF) disorder, continues to present a clinical challenge regarding the optimal choice between immunosuppressive therapy (IST) and hematopoietic stem cell transplantation (HSCT). During the recent European Society for Blood and Marrow Transplantation (EBMT) meeting, Professor Antonio Risitano provided a comprehensive overview of the Severe…
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Safety Profiles in the Real World: An EBMT Registry Study on the Evolution of Non-Relapse Mortality in 6,928 CAR-T Recipients
The advent of Chimeric Antigen Receptor T-cell (CAR-T) therapy has fundamentally transformed the treatment landscape for relapsed/refractory (R/R) hematologic malignancies. However, as clinical adoption expands and follow-up durations extend, the management of treatment-related toxicities—specifically Non-Relapse Mortality (NRM)—has emerged as a critical bottleneck for long-term patient survival. At the 2026 Annual Meeting of the European Society…
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Filling the Void in Myeloid Neoplasm Evaluation: Prof. Donal McLornan on Defining Remission, Relapse, and Outcome Optimization in MDS/MPN Overlap Syndromes
llogeneic hematopoietic cell transplantation (allo-HCT) remains the only potentially curative intervention for Myelodysplastic Syndromes/Myeloproliferative Neoplasm (MDS/MPN) overlap syndromes. However, due to the high heterogeneity and low incidence of these disorders, the clinical field has long lacked unified criteria for evaluating post-transplant remission and relapse. At the recent European Society for Blood and Marrow Transplantation (EBMT)…
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Deciphering VEXAS Syndrome: From UBA1 Somatic Mutations to Precision Management and Allo-HSCT
During the recent workshop “Focus on Allogeneic HSCT in Myelodysplastic Syndromes,” Professor Fabio Ciceri (IRCCS San Raffaele Scientific Institute / Vita-Salute San Raffaele University), Chair of the EBMT Scientific Council and the Acute Leukemia Working Party (ALWP), provided a comprehensive overview of “Contemporary Approaches to VEXAS.” He systematically detailed the genetic foundations, clinical progression, and…
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