In 2025, the highly anticipated 30th European Hematology Association (EHA) Annual Congress was grandly held in Milan, Italy. This conference brought together top experts and scholars from around the world to discuss cutting-edge topics in basic research and clinical translation in the field of hematolog.Professor Daniel Hartson from the University of Cambridge delivered an insightful presentation on "Deciphering the Genomics of Aggressive Lymphoma." He systematically elaborated on the genetic complexity of Diffuse Large B-cell Lymphoma (DLBCL), shared his team's breakthrough achievements in constructing novel functional genomics models, and emphasized the critical importance of standardized molecular profiling for advancing future clinical research and personalized medicine.