On December 7th, local time, the highly anticipated session on the "Updated ASH Clinical Practice Guidelines on Acute Myeloid Leukemia (AML) in Older Adults" was successfully held at the American Society of Hematology (ASH) Annual Meeting. This session was chaired by Professor Mikkael Sekeres, the lead expert of the ASH guidelines and Director of the Department of Hematology at Sylvester Comprehensive Cancer Center. To gain deeper insights into the key points of the guideline update and the emerging trends it reflects, Oncology Frontier- Hematology Frontier invited Professor Huafeng Wang from Zhejiang University School of Medicine’s First Affiliated Hospital to engage in a deep dialogue with Professor Sekeres.