Dr. Chun-rong Ju: Lung Transplant Recipients Receive Prolonged Contezolid Treatment for Nocardia InfectionDr. Chun-rong Ju: Lung Transplant Recipients

Dr. Chun-rong Ju: Lung Transplant Recipients Receive Prolonged Contezolid Treatment for Nocardia InfectionDr. Chun-rong Ju: Lung Transplant Recipients

Nocardia is a conditional pathogen, and infections are common in immunocompromised populations such as organ transplant recipients. Professor Chunrong Ju and her team at the First Affiliated Hospital of Guangzhou Medical University's Respiratory and Critical Care Department and Transplant Department previously reported cases of Nocardia infection in lung transplant recipients (LTR) among the East Asian population [1,2]. During the 2023 IDWeek congress, Dr. Chun-rong Ju further presented the clinical outcomes of 18 LTR Nocardia infection patients who received treatment with the novel oxazolidinone-class drugs Linezolid or Contezolid. The results indicated that these novel oxazolidinone drugs were effective during prolonged anti-infection therapy in such patients and had fewer toxic side effects, including bone marrow suppression [3].
ESMO Live Update | Dr. Girard Analyzes PAPILLON: Opening New Doors for First-Line Treatment of EGFR Exon 20 Insertion Mutant Advanced NSCLC

ESMO Live Update | Dr. Girard Analyzes PAPILLON: Opening New Doors for First-Line Treatment of EGFR Exon 20 Insertion Mutant Advanced NSCLC

Based on the results of the PAPILLON trial, presented at the 2023 ESMO Congress, a dual-specificity EGFR/MET monoclonal antibody has the potential to become a standard of care for EGFR exon 20 insertion mutant advanced or metastatic non-small cell lung cancer (NSCLC), although toxicity management must be approached with caution (Abstract LBA5). Dr. Nicolas Girard, the lead author of the study and a researcher at the Curie-Montsouris Thoracic Institute, discussed the implications of these findings for clinical practice in an interview with Oncology Insight conducted during the conference.