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Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Refractory/Relapsed Diffuse Large B-cell Lymphoma Patients with Failure of CAR-T Therapy
In the challenging field of hematology, the search for effective treatments for relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL) after CAR-T therapy failure is crucial. Professor Professor Haiwen Huang from The First Affiliated Hospital of Soochow University leads an innovative study exploring allogeneic hematopoietic stem cell transplantation (allo-HSCT) as a promising alternative. This…
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Dr.Taisheng Li’s Team Presents the “Chinese Solution” for HIV Immune Reconstitution Deficiency at CROI 2024
At the 31st Conference on Retroviruses and Opportunistic Infections (CROI 2024) held from March 3 to 6 in Denver, Colorado, USA, a study by Dr. Taisheng Li’s team from the Peking Union Medical College Hospital was selected for a poster presentation and discussed at the fifth session. This conference, which started in 1993, has become…
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Dr. Shuihua Lu: First RCT Study Reported on a Novel Vaccine for Preventing Tuberculosis Relapse丨CROI Commentary
Patients who have successfully completed tuberculosis treatment still face a high risk of relapse, making the development of vaccines to prevent recurrent pulmonary tuberculosis an important direction in TB prevention efforts. At the recently concluded 31st Conference on Retroviruses and Opportunistic Infections (CROI 2024), a study presented as a late-breaking abstract (Abstract Number: 210) revealed…
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Dr. Shuihua Lu: Trends in PAN-TB Treatment and Mid-term Report Review on QDB Study丨CROI Commentary
In recent years, the concept of PAN-TB treatment, representing a comprehensive approach to tuberculosis (TB) therapy, has seen numerous developmental breakthroughs. This universal treatment method is applicable to all types of TB patients and is not limited by the resistance of traditional anti-tuberculosis drugs (i.e., there’s no need to test for drug resistance), offering advantages…
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Dr. Hui Wang: Long-acting Cabotegravir Maintains High Efficacy in Preventing HIV Among Populations with High Incidence of Bacterial STIs丨CROI Commentary
The association between sexually transmitted infections (STIs) and HIV infection has always been a focal point in the medical community. With the promotion of pre-exposure prophylaxis (PrEP) strategies to prevent HIV infection, the impact of STIs on the effectiveness of PrEP has become an urgent issue to address. At the recently concluded Conference on Retroviruses…
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Dr. Shuihua Lu: Advances in Short-course Treatment for Drug-Sensitive Tuberculosis and Commentary on the CLO-FAST Study丨CROI Commentary
Editor’s Note: In recent years, the quest for shorter treatment durations and more effective drug combinations to treat drug-sensitive tuberculosis (DS-TB) has become a major research trend in the field…
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Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma
Professor Haiwen Huang from The First Affiliated Hospital of Soochow University provided an enlightening discourse on the significant strides made in CAR T cell therapies, with a special emphasis on their pioneering work in FcRH5 CAR-T cells for multiple myeloma. The study not only showcased the remarkable journey of hematology research over the years but…
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Orelabrutinib for the treatment of relapsed or refractory marginal zone lymphoma: A phase 2, multicenter, open-label study
In the evolving landscape of hematology and oncology, innovative treatments for challenging conditions like relapsed or refractory marginal zone lymphoma are of paramount importance. It is in this context that the recent phase 2, multicenter, open-label study investigating the efficacy of Orelabrutinib comes to light, marking a significant advancement in the therapeutic domain. This study,…
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