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Breaking Through – Promising Results from Phase I Study of KSD-101 Dendritic Cell Vaccine in Treating EBV-Positive Hematologic Malignancies
Epstein-Barr virus (EBV) infection is widespread among adults, yet there is no standard treatment for EBV-positive hematologic malignancies, leading to poor patient outcomes. At the 29th Annual Meeting of the European Hematology Association (EHA), Professor Chunrui Li from Tongji Hospital of Huazhong University of Science and Technology presented the results of her team’s Phase I…
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EHA 5-Minute Interview | Professor Minghui Duan: Latest Advances in Myelofibrosis Treatment
Myeloproliferative neoplasms (MPNs) are a group of clonal hematopoietic stem cell disorders, including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (MF). At the 29th European Hematology Association (EHA) Annual Meeting held in Madrid, Spain, from June 13 to 16, 2024, notable advancements were made in MPN research. Oncology Frontier-Hematology Frontier invited Professor Minghui…
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Rare Cause of Splenic Infarction with Cholestasis-Related Liver Failure: A Case of Diffuse Large B-Cell Lymphoma
To help clinical hepatologists broaden their horizons and enrich their practical experience, the Hepatology Digest journal has invited Professor Shanhong Tang’s team from the Department of Gastroenterology at General Hospital of Western Theater Command to create the “Liver Challenging Cases” column. This column compiles classic cases encountered by Professor Tang’s team over years of clinical…
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APACC On-site Report | Dr. Ye Zhang: “Pay it Forward” – A New Strategy to Increase STD Testing Rates
In the era of 5G, the consumption and entertainment habits of sexually active young people have changed significantly, including activities such as drinking coffee, shopping, watching movies, and taking selfies. It is essential to continuously explore and improve strategies for testing and preventing sexually transmitted diseases (STDs) that are tailored to the times and local…
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Dr. Brigitte Quenum: Breaking the “isolated island” model and integrating resources to address HIV prevention and control challenges in Asia and the Pacific
Recently, at the 9th Asia-Pacific AIDS& Co- Infections Conference 2024 (APACC 2024), Dr. Brigitte Quenum, UNAIDS Regional Office for Asia and the Pacific, delivered a speech entitled “Challenges & Success in the Region” and in an interview with Infectious Disease Frontier,she introduced the challenges and solutions of HIV/AIDS prevention and treatment in the Asia- Pacific…
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Professor Jun Cheng: New Strategy for Clearing HBV cccDNA, but Further Validation Needed
Clinical cure of chronic hepatitis B (CHB), also known as functional cure, is achieved when patients remain HBsAg negative after stopping treatment, with or without the presence of anti-HBs, HBV DNA levels below the detection limit, and normal liver biochemical indicators. However, HBV covalently closed circular DNA (cccDNA) may still persist in the nuclei of…
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Xinghai Forum: Professors Hong Hu and Yuntao Wei Discuss CDK4/6 Inhibitors in Adjuvant Therapy for HR+ Breast Cancer
Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have brought transformative breakthroughs to the clinical treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer patients. The combination of CDK4/6 inhibitors and endocrine therapy has become the standard regimen for HR+/HER2- locally advanced and metastatic breast cancer. In the adjuvant treatment phase for early-stage…
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APACC Live Report: Dr. Rongqiu Liu from Professor Hua You’s Team Shares Research Findings and Management Strategies for HIV-Associated Malignancies
For HIV patients, encountering malignancies is akin to a double blow, exacerbating their already challenging condition. HIV-infected individuals commonly face opportunistic diseases such as diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL). Enhancing early diagnosis and treatment of HIV-associated tumors and refining clinical management strategies are critical areas for clinical and research exploration. At…
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