On November 14, 2025, the Second International Cell and Immunotherapy Congress convened in Hangzhou. The meeting is co-chaired by He Huang from the First Affiliated Hospital of Zhejiang University School of Medicine and Mohamad Mohty, President of the International Academy for Clinical Hematology (IACH). Clinical experts, basic researchers, young scientists, and representatives from biopharmaceutical enterprises gathered from around the globe to engage in in-depth discussions on the latest advances in cell and immunotherapy. The congress not only showcased cutting-edge scientific achievements but also fostered meaningful interdisciplinary collaboration, illuminating key directions for future innovation in cell therapy, immunotherapy, and hematologic research. Oncology Frontier – Hematology Frontier Update has compiled highlights from the first day of the conference to share this academic event with colleagues and explore new frontiers in the field together.