Microbiota Modulation: A New Pillar in aGVHD Treatment 

Microbiota Modulation: A New Pillar in aGVHD Treatment 

Professor Mohamad Mohty, Head of the Hematology and Cellular Therapy Department at Saint-Antoine Hospital and Sorbonne University, Paris, discusses a paradigm shift in managing acute graft-versus-host disease (aGVHD).He highlights the critical role of gut microbiota dysbiosis in the pathogenesis of aGVHD following allogeneic hematopoietic stem cell transplantation and elaborates on the therapeutic potential of microbiota modulation. 
A New Era for AML Treatment: Integrating Novel Therapies and Global Collaboration 

A New Era for AML Treatment: Integrating Novel Therapies and Global Collaboration 

Professor Norbert Claude Gorin, the first Chair of the Global Committee of the European Society for Blood and Marrow Transplantation (EBMT), discussed the evolution of transplantation strategies for Acute Myeloid Leukemia (AML) and the importance of international cooperation. In an interview with Hematology Frontier during the second 2025 CTI conference in Hangzhou, he highlighted how decades of progress have reshaped the treatment landscape. 
Bringing Together Global Expertise to Advance Uro-Oncology

Bringing Together Global Expertise to Advance Uro-Oncology

During the 2025 ESMO Congress, the first and only ESMO-authorized “ESMO China Focus” Uro-Oncology Session was successfully held on October 19 in Berlin. The forum highlighted major advances in urothelial carcinoma and prostate cancer, bringing together Chinese and international experts for in-depth academic discussions and intellectual exchange. Experts agreed that data from landmark studies such as EV-302 and EV-103 firmly establish enfortumab vedotin (EV)–based combination therapy as the new first-line standard of care for locally advanced or metastatic urothelial carcinoma (La/mUC). In addition, androgen-receptor pathway inhibitors (ARPI), represented by enzalutamide—which remains the only ARPI with 8-year overall-survival follow-up—continue to redefine long-term survival expectations for patients with prostate cancer, marking a new era for uro-oncology.
When the breeze rises over West Lake and wisdom sends ripples across the world, when the Qiantang tide surges and innovation breaks waves toward a new era— the 2025 International Cell and Immunotherapy Congress officially opens 

When the breeze rises over West Lake and wisdom sends ripples across the world, when the Qiantang tide surges and innovation breaks waves toward a new era— the 2025 International Cell and Immunotherapy Congress officially opens 

On November 14, 2025, the Second International Cell and Immunotherapy Congress convened in Hangzhou. The meeting is co-chaired by He Huang from the First Affiliated Hospital of Zhejiang University School of Medicine and Mohamad Mohty, President of the International Academy for Clinical Hematology (IACH). Clinical experts, basic researchers, young scientists, and representatives from biopharmaceutical enterprises gathered from around the globe to engage in in-depth discussions on the latest advances in cell and immunotherapy. The congress not only showcased cutting-edge scientific achievements but also fostered meaningful interdisciplinary collaboration, illuminating key directions for future innovation in cell therapy, immunotherapy, and hematologic research. Oncology Frontier – Hematology Frontier Update has compiled highlights from the first day of the conference to share this academic event with colleagues and explore new frontiers in the field together.