• In-Depth Analysis丨Dr. Wei Li & Dr. Shaohua Zhang: First-Line Treatment Options for Patients with Recurrent Metastatic Triple-Negative Breast Cancer

    For patients with recurrent metastatic triple-negative breast cancer (TNBC), would you choose “chemotherapy + immunotherapy” or “ADC” for treatment? At the 2024 Breast Cancer Summer Forum·Northern Salon “In-Depth Analysis” session, Dr. Wei Li from Jiangsu Provincial People’s Hospital and Dr. Shaohua Zhang from the Chinese PLA General Hospital presented their respective viewpoints. Dr. Wei Li…

  • Exclusive Interview with Dr. Jian Zhou, Chairman of the APPLE Alliance丨Global Liver Cancer: “Look East” to Integrate More Chinese Wisdom and Strengt

    At the recent 14th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2024), Dr. Jian Zhou from Zhongshan Hospital, Fudan University, officially assumed the position of the new Chairman of the Asia-Pacific Primary Liver Cancer Expert Association (APPLE). This marks the first time since the establishment of the APPLE Alliance that a Chinese mainland expert has…

  • JOH丨GLP-1R/GCGR Dual Agonist Offers New Approach for Treating MASLD

    It is estimated that 25% of adults worldwide are affected by metabolic dysfunction-associated steatotic liver disease (MASLD). MASLD is characterized by at least 5% liver fat content in individuals who do not consume alcohol or consume very little. MASLD represents the liver manifestation of metabolic syndrome and is closely associated with obesity, insulin resistance, and…

  • N-Glycan Markers for Non-Invasive Diagnosis of Liver Fibrosis

    As of 2022, there are 257.5 million people worldwide who are HBsAg positive. Decompensated cirrhosis and hepatocellular carcinoma (HCC) are the leading causes of death among chronic HBV patients. Liver biopsy is the “gold standard” for diagnosing fibrosis stages, but its invasive nature makes many patients reluctant to undergo the procedure. Recently, a study published…

  • AIDS 2024丨In the Era of U=U, Australia’s SVS Rate Among HIV Patients Exceeds 95%

    In recent years, the concept of “U=U” (Undetectable equals Untransmittable) has become widely recognized in the field of HIV prevention. This concept is based on extensive scientific research showing that HIV patients on effective antiretroviral therapy (ART) who achieve and maintain an undetectable viral load (typically defined as less than 20 or 50 copies/mL) have…

  • AIDS Review丨Dr. Yun He: Doxycycline PrEP Reduces STI Incidence in People with HIV

    The 25th International AIDS Conference was held from July 22-26, 2024, in Munich, Germany. At the conference, a randomized controlled trial conducted by the Canadian Centre for Disease Control, the University of British Columbia, and the Canadian HIV Trials Network evaluated the effectiveness of doxycycline pre-exposure prophylaxis (doxyPrEP) in preventing bacterial sexually transmitted infections (STIs)…

  • Meeting Summary on Optimizing Pediatric Tuberculosis Drugs

    Children are the future of humanity and an essential resource for sustainable social development. However, approximately 1.2 million children and adolescents worldwide are threatened by tuberculosis (TB), with drug-resistant TB complicating treatment. To optimize pediatric TB drug treatment strategies, the World Health Organization (WHO) held the second Pediatric Drug Optimization for Tuberculosis (PADO-TB) meeting from…

  • Antimalarial Drugs as Potential Treatment for Polycystic Ovary Syndrome

    Recently, a groundbreaking study published in Science has revealed that the antimalarial drug artemisinin may have potential therapeutic effects on polycystic ovary syndrome (PCOS). PCOS is a complex endocrine disorder primarily affecting women of reproductive age. It is characterized by persistent anovulation, hyperandrogenism, and insulin resistance. Clinically, it manifests as irregular menstrual cycles, enlarged ovaries…