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Dr. Jing Sun: SYK Inhibitors Set Sail at EHA – Solepinib’s Dual Mechanism Offers New Hope for ITP Treatment
The annual meeting of the European Hematology Association (EHA) is an international conference in the field of hematology, bringing together numerous experts and scholars from around the world to share and delve into innovative ideas and research progress, promoting continuous development in the field of hematology. This year, the research achievements of spleen tyrosine kinase…
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Portal Pressure Gradient 24 Hours Post-TIPS Provides More Accurate Risk Prediction for Complications
Portal hypertension is a severe complication of chronic liver disease, directly associated with clinical outcomes such as ascites and variceal bleeding. Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment that significantly reduces portal pressure. Portal pressure gradient (PPG) is commonly used to assess portal pressure in patients undergoing TIPS. Recently, a study led by…
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Interventional Therapy in Hepatobiliary Diseases | Dr. Xuefeng Luo: In-depth Analysis of the French Guidelines on Transjugular Intrahepatic Portosyste
Interventional therapy is an emerging clinical discipline and an important part of minimally invasive medicine. It stands as the third major clinical discipline, distinct from traditional internal medicine and surgery. Interventional therapy allows the treatment of various diseases through tiny channels a few millimeters in diameter created in the skin, using advanced imaging technologies such…
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Dynamic Changes in Circulating Tumor DNA in Hepatocellular Carcinoma Patients Reveal Its Potential as a Non-Invasive Biomarker
A recent clinical study conducted by Dr. Jean-Charles Nault and his team at the Cordeliers Research Center of Sorbonne University, France, was published in Gut journal. This study reveals the dynamic changes in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC) and its clinical significance. The findings provide new perspectives and tools for…
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Newly Released! IDSA 2024 Guidelines for Treating Resistant Gram-Negative Bacterial Infections
As antimicrobial resistance (AMR) continues to be a growing global public health challenge, treating infections caused by resistant bacteria has become increasingly difficult. Recently, the Infectious Diseases Society of America (IDSA) released the “IDSA 2024 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections,” providing clinicians with valuable treatment recommendations. This document primarily addresses infections…
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Dr. Steven Narod: Bilateral Mastectomy and Breast Cancer Mortality—A Rethink of Clinical Guidelines
In recent years, bilateral mastectomy, as a surgical approach to prevent contralateral breast cancer, has gained a certain degree of attention and application. However, there is still controversy regarding the actual effectiveness of bilateral mastectomy in preventing breast cancer mortality. Recently, Dr. Steven Narod from the Dalla Lana School of Public Health published a research…
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International Perspective丨Weighing the Risks of Chemotherapy: Is Chemotherapy Necessary for Adjuvant and Stage IV NSCLC Treatment?
The necessity of adding chemotherapy to postoperative adjuvant treatment and in Stage IV non-small cell lung cancer (NSCLC) remains a topic of debate. In this article, Dr. Mark G. Kris from Memorial Sloan Kettering Cancer Center analyzes the value of chemotherapy in the adjuvant treatment of early-stage NSCLC with EGFR and ALK mutations, as well…
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International Perspective丨What Challenges Does Immunotherapy Face in Early-Stage NSCLC?
The successes of immunotherapy and targeted therapy in metastatic non-small cell lung cancer (NSCLC) have raised hopes for implementing these therapies in earlier stages of the disease. Recent trial results indicate that neoadjuvant, adjuvant, and perioperative immunotherapy may improve the cure rates of early-stage NSCLC. While early diagnosis of patients could make immunotherapy a significant…