IOncology

The 47th San Antonio Breast Cancer Symposium (SABCS) was grandly held from December 10–13, 2024, in San Antonio, USA, showcasing significant global advancements in breast cancer research. During the conference, Dr. Xiaojia Wang from the Cancer Hospital of the University of the Chinese Academy of Sciences (Zhejiang Cancer Hospital) presented several important research findings. These included innovative treatment strategies with the new PD-1/VEGF bispecific antibody Ivosidenib and the novel antibody-drug conjugate (ADC) ARX788. Additionally, multiple real-world studies (RWS) provided valuable clinical insights into intensified adjuvant therapy for early-stage HER2-positive breast cancer, systemic therapy for advanced breast cancer, and breast cancer bone metastases. These contributions amplified the voice of China in breast cancer research at SABCS.Oncology Frontier interviewed Dr. Xiaojia Wang at the conference to share key data from these studies.

The de-escalation strategy for axillary management in breast cancer has been a consistent research focus in breast surgery. Last year, the SOUND study explored whether certain low-risk patients undergoing breast-conserving surgery could avoid sentinel lymph node biopsy (SLNB). At the 2024 San Antonio Breast Cancer Symposium (SABCS), the INSEMA study, a similar investigation, was presented. Oncology Frontier invited Dr. Yiding Chen from The Second Affiliated Hospital of Zhejiang University School of Medicine to provide an in-depth analysis of the INSEMA study.

The "2024 Yixian Breast Cancer Conference and the Second China Young Breast Cancer Consensus Conference" took place in Guangzhou from December 27 to 28, 2024. The conference explored cutting-edge topics such as the evolving epidemiology of young breast cancer, screening strategies, the impact of genetic mutations, treatment, and recovery approaches. Highlights included the release of the YBCC Consensus on Diagnosis and Treatment (Patient Edition), the China Genetic Mutation Pathogenicity Database, and the Young Breast Cancer Quality of Life Scale. Oncology Frontier interviewed Dr. Qiang Liu, the conference chair from Sun Yat-sen Memorial Hospital, Sun Yat-sen University, to discuss key highlights, the unique epidemiological characteristics of young breast cancer, and future plans for advancing standardized care in this area.

On December 28, 2024, the year-end meeting of the Youth Expert Committee of the Chinese Society of Clinical Oncology (CSCO) was successfully held in Shanghai. This event brought together renowned experts and promising young talents from across the country to explore new directions in cancer treatment. Oncology Frontier had the honor of interviewing Dr. Biyun Wang, Chair of the conference and a leading expert at Fudan University Shanghai Cancer Center, who shared key highlights of the conference, insights on the development of young oncologists, the achievements of CSCO YOUNG, and future plans.

As the year draws to a close, reflection and progress take center stage. The "2024 Beijing Forbidden City Annual Lung Cancer Conference and the 16th Multidisciplinary Seminar on Advances in Lung Cancer Diagnosis and Treatment," jointly organized by the Beijing Tumor Prevention and Research Association, the China Association of Senior Healthcare, the Beijing Medical Love Public Welfare Foundation, and the Beijing Chen Jumei Public Welfare Foundation, was successfully held on December 13–14, 2024, in Beijing.

Dr. Ming Zhao shares key insights on combining local and systemic therapies to improve liver cancer treatment outcomes. Learn how innovative approaches like immunotherapy and targeted treatments are transforming patient care.

The 2024 Yixian Breast Cancer Conference and the 2nd China Young Breast Cancer Consensus Conference, held on December 27–28 in Guangzhou, brought together leading experts in breast disease to discuss the latest advancements in treatment and management. The conference also focused on consensus guidelines for diagnosing and treating young breast cancer patients, aiming to improve cure rates and rehabilitation outcomes. At the event, Dr. Rui Xu from the Breast Specialty Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine shared cutting-edge findings in breast cancer surgery, offering new perspectives for treatment. In an interview with Oncology Frontier, Professor Xu provided an overview of the latest surgical advancements and developments in integrative medicine for breast cancer.

In 2024, Professor Wu Yilong a luminary in the field of lung cancer and a cornerstone of Oncology Frontier, exemplified unwavering commitment to advancing medical care and education. from leading…

In recent years, breakthroughs in basic research and clinical trials, particularly in combined targeted and immunotherapy strategies and the development of domestically produced novel drugs, have significantly advanced clinical practices in uro-oncology. However, transforming cutting-edge research into practical clinical applications and sharing Chinese expertise with international patients remains an ongoing challenge. The 14th Shanghai Genitourinary Oncology Academic Conference and Annual Meeting of Chinese Anti-Cancer Association—Genitourinary Oncology Committee (CACA-GO) were held in Shanghai from December 6 to 8. Following the event, Urology Frontier invited Professor Dingwei Ye, the conference chair and leading expert from Fudan University Shanghai Cancer Center, to share the highlights and experiences of this impactful event.

In the treatment landscape of HR+/HER2- metastatic breast cancer (MBC), CDK4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) have become a widely used first-line treatment. However, patients with symptomatic visceral metastases often opt for chemotherapy (CT). While some prospective studies suggest that CDK4/6i + ET may yield better outcomes even in patients with visceral metastases, no studies have explored these strategies in real-world settings.