Individualized Treatment of Prostate Cancer and Clinical Management of NHT-Related Adverse Effects

Individualized Treatment of Prostate Cancer and Clinical Management of NHT-Related Adverse Effects

In the era of precision medicine for prostate cancer, individualized clinical decision-making has become a central focus of daily practice. At a recent academic conference on urologic oncology, Professor Hailiang Zhang from Huadong Hospital affiliated with Fudan University shared his clinical perspectives on novel hormonal therapy (NHT) in metastatic prostate cancer. He emphasized that, based on solid evidence from randomized clinical trials, NHT combined with androgen deprivation therapy (ADT) has become the standard first-line treatment for both metastatic hormone-sensitive prostate cancer (mHSPC) and metastatic castration-resistant prostate cancer (mCRPC). Nevertheless, optimal treatment selection requires an integrated assessment of tumor burden, genomic characteristics, patient age, and comorbidities, enabling a truly “tailor-made” approach.
Lymphoma Roundtable · ASH Special | Professor Cai Qingqing: New Advances in the Treatment of Relapsed/Refractory Follicular Lymphoma

Lymphoma Roundtable · ASH Special | Professor Cai Qingqing: New Advances in the Treatment of Relapsed/Refractory Follicular Lymphoma

The 2025 Annual Meeting of the American Society of Hematology (ASH 2025) has recently concluded successfully in Orlando, USA. As the “grand finale” of the hematology field each year, this meeting showcased a series of cutting-edge breakthroughs in lymphoma research, providing new directions for optimizing clinical practice.
Breaking Diagnostic Bottlenecks: The IBMDX Study Reveals 37% Diagnostic Yield and Health Economic Value of Whole Genome Sequencing (WGS) in Inherited Bone Marrow Failure Syndromes

Breaking Diagnostic Bottlenecks: The IBMDX Study Reveals 37% Diagnostic Yield and Health Economic Value of Whole Genome Sequencing (WGS) in Inherited Bone Marrow Failure Syndromes

At the 2025 American Society of Hematology (ASH) Annual Meeting, Dr. Lucy Fox from the Peter MacCallum Cancer Centre (Australia) presented the highly anticipated results of the IBMDX study. This landmark trial evaluated the clinical utility and economic impact of "Upfront Whole Genome Sequencing (WGS)" in patients with suspected Inherited Bone Marrow Failure Syndromes (IBMFS). The findings suggest a paradigm shift is underway: WGS not only achieves a diagnostic yield of 37%—surpassing traditional panels and exome sequencing—but also uncovers complex genomic mechanisms previously invisible to standard testing.
ASH China Voice | Prof. Yajing Zhang: Exploring Frontiers and Synergistic Innovation—A Multidimensional and Strategic Vision for CAR-T Therapy

ASH China Voice | Prof. Yajing Zhang: Exploring Frontiers and Synergistic Innovation—A Multidimensional and Strategic Vision for CAR-T Therapy

The 67th Annual Meeting of the American Society of Hematology (ASH) was held in Orlando from December 6 to 9, 2025, bringing together the latest global advances in hematologic research and clinical practice. At this year’s meeting, four studies led by Prof. Yajing Zhang from Beijing Gobroad Boren Hospital were accepted, including one oral presentation.