The 66th American Society of Hematology Annual Meeting (ASH)

The 66th American Society of Hematology Annual Meeting (ASH)

The 66th American Society of Hematology Annual Meeting (ASH) was grandly held in San Diego, USA, from December 7th to 10th, 2024. This annual event is one of the most influential scientific communication platforms in the field of hematology worldwide. This edition of the ASH Annual Meeting attracted over 25,000 professionals, including clinicians, scientists, researchers, and healthcare decision-makers from more than 100 countries around the globe. The conference covered all aspects of malignant and non-malignant hematology, from basic scientific research to clinical practice, from drug development to therapeutic innovation, reflecting the latest advancements and future trends in the field of hematology.
The 8th West China Uro-Oncology Tianfu Academic Conference丨Dr. Yige Bao: Perioperative Personalized Treatment of UTUC Based on ADC Drugs and the West

The 8th West China Uro-Oncology Tianfu Academic Conference丨Dr. Yige Bao: Perioperative Personalized Treatment of UTUC Based on ADC Drugs and the West

Upper tract urothelial carcinoma (UTUC), encompassing renal pelvic and ureteral cancers, is relatively rare, with unique characteristics in the Chinese population, such as distinct disease features and molecular biology profiles. The 8th West China Uro-Oncology Tianfu Academic Conference, recently held in Chengdu, provided a platform to discuss how to better address the challenges in UTUC treatment and improve patient outcomes. In this event, Oncology Frontier interviewed Dr. Yige Bao from West China Hospital of Sichuan University, who shared insights into personalized perioperative treatment of UTUC with ADC drugs and the hospital's clinical experiences.
CCHIO 2024丨Dr. Gang Zhu: Enhancing Patient Rehabilitation Concepts and Individualized Treatment for Multistage Benefits in Prostate Cancer Patients

CCHIO 2024丨Dr. Gang Zhu: Enhancing Patient Rehabilitation Concepts and Individualized Treatment for Multistage Benefits in Prostate Cancer Patients

With economic development, lifestyle changes, and environmental factors, prostate cancer incidence in China has significantly increased. Screening high-risk populations and providing precision treatment and rehabilitation support based on patient characteristics are crucial for improving cure rates and quality of life. At the 2024 Chinese Congress of Holistic Integrative Oncology (CCHIO), Dr. Gang Zhu, Chair of the Urological Oncology Rehabilitation Committee of the Chinese Anti-Cancer Association and Director of General Surgery and Urology at United Family Healthcare, presented insights on individualized treatment for prostate cancer. Urology Frontier had the opportunity to delve deeper into this topic with Professor Zhu.
An Exploratory Analysis of the PRESERVE 1Trial: Assessing Trilaciclib’s Role in Reducing Chemotherapy-Related Toxicity in Metastatic Colorectal Cancer

An Exploratory Analysis of the PRESERVE 1Trial: Assessing Trilaciclib’s Role in Reducing Chemotherapy-Related Toxicity in Metastatic Colorectal Cancer

On November 23rd, Dr. Tianshu Liu's team from Zhongshan Hospital published a study titled "Trilaciclib prior to FOLFOXIRI/bevacizumab for patients with untreated metastatic colorectal cancer: phase 3 PRESERVE 1 trial" in JNCI Cancer Spectrum(IF=3.4). The PRESERVE 1 trial sheds light on trilaciclib's potential to reduce chemotherapy-related toxicity in mCRC. While its efficacy in mitigating myelosuppression is evident, the antitumor results are concerning. Further studies are needed to explore the balance between toxicity reduction and efficacy, and to determine trilaciclib's optimal use in cancer treatment.
CCHIO 2024 | Dr. Bicheng Zhang: Post-Resistance Strategies for Third-Generation EGFR-TKIs in NSCLC

CCHIO 2024 | Dr. Bicheng Zhang: Post-Resistance Strategies for Third-Generation EGFR-TKIs in NSCLC

EGFR mutations are among the most common genetic abnormalities in non-squamous non-small cell lung cancer (NSCLC), and EGFR-TKIs have become the standard first-line treatment for advanced EGFR-mutant NSCLC. Despite significant advancements across three generations of EGFR-TKIs, resistance remains unavoidable. Post-resistance treatment options for EGFR-TKI patients, particularly those facing complex third-generation resistance mechanisms, are limited.
CCHIO 2024 | Dr. Xiuyi Zhi: Systematizing Popular Science Efforts to Enhance Public Knowledge, Trust, and Action in Cancer Prevention and Control

CCHIO 2024 | Dr. Xiuyi Zhi: Systematizing Popular Science Efforts to Enhance Public Knowledge, Trust, and Action in Cancer Prevention and Control

The 2024 Chinese Congress on Holistic Integrative Oncology (CCHIO) concluded on November 17, emphasizing a multidisciplinary approach to oncology. The event featured specialized sessions on integrated rehabilitation, public education, and cancer prevention, showcasing novel perspectives and techniques for comprehensive cancer care. During the conference, Oncology Frontier had the honor of interviewing Dr. Xiuyi Zhi, Chief Expert of Thoracic Surgery at Xuanwu Hospital, Capital Medical University, and Director of the Public Education Department of the Chinese Anti-Cancer Association (CACA). Professor Zhi shared the progress in cancer education initiatives and the development of cancer prevention awareness in China.

CCHIO 2024丨Dr. Xiufeng Liu: Exploring the Clinical Potential of the “Cola Combination” from LEAP-002 to LEAP-012

The era of immunotherapy has brought new hope to advanced hepatocellular carcinoma (HCC), with various targeted-immune combination therapies emerging as potential breakthroughs. However, the journey of the "Cola Combination"—pembrolizumab combined with lenvatinib—has been marked by mixed results. In the LEAP-002 trial, the combination showed negative results in the general population but positive outcomes in the Asian subgroup. The LEAP-012 trial further demonstrated the combination's efficacy when paired with transarterial chemoembolization (TACE) in intermediate-stage HCC. Yet, its precise role in clinical practice remains under discussion.
CTI 2024 | Dr. Ibrahim Yakoub-Agha Discusses the Application of Cellular Immunotherapy in Myelofibrosis

CTI 2024 | Dr. Ibrahim Yakoub-Agha Discusses the Application of Cellular Immunotherapy in Myelofibrosis

From November 14th to 17th, 2024, the Cellular Therapy and Immunotherapy Conference (CTI) was grandly held in Hangzhou, China, gathering top experts, scholars, and industry leaders in the fields of cell therapy and immune therapy from around the world. The conference served not only as an international platform for academic exchange but also as an important window to showcase the latest scientific research and promote the development of the field. During the conference, "Hematology Frontier" specially invited Dr. Ibrahim Yakoub-Agha from the Lille University , France, to reveal the unlimited potential and broad prospects of cellular immunotherapy in myelofibrosis.