EBMT Global Perspective | Professor Donal McLornan: Defining Remission Criteria and Optimizing Novel Combination Strategies for Bone Marrow Transplantation in MDS/MPN Overlap Syndromes
Myelodysplastic/myeloproliferative neoplasm (MDS/MPN) overlap syndromes are rare hematologic malignancies characterized by marked clinical heterogeneity and significant diagnostic and therapeutic challenges. Allogeneic hematopoietic stem cell transplantation remains a key treatment option; however, the lack of standardized criteria for assessing post-transplant remission and relapse represents a major unmet clinical need.