December 2023 - Page 5 of 8

AASLD Interview | Professor Bernd Schnabl: Delving into the “Gut-Liver Axis,” Decoding the Role of Gut Microbiota in the Diagnosis and Treatment of Autoimmune Liver Diseases

By Mourabit Halima 2023.12.14

The gut microbiome, a complex ecosystem within the human intestinal tract, has a broad impact on physiological functions. Gut microbiome imbalance has become one of the most critical environmental factors in the onset of chronic inflammatory diseases. The liver is one of the first identified targets of autoimmune attack. In recent years, with deeper research into the gut microbiome, the relationship between gut microbiota and liver diseases has gained increasing attention. Studies have found that gut microbiota might play a role in the development and progression of autoimmune liver diseases, making the treatment of gut microbiota imbalance a potential key target.

AASLD Interview丨Professor Jeffrey V. Lazarus: Clinical Management, Research Priorities, and Future Action Plans for MASLD

By Mourabit Halima 2023.12.14

The 2023 American Association for the Study of Liver Diseases (AASLD 2023) recently concluded in Boston, USA. metabolic dysfunction-associated steatotic liver disease (MASLD) was a key topic at the conference. In the "Healthy Liver, Healthy Lives" session, experts discussed how to reverse the global MASLD trend and what actions to take to address MASLD management challenges. Dr. Jeffrey V. Lazarus, head of the Health Systems Research Group at ISGlobal in Barcelona, Spain, attended the meeting and gave an interview to "Hepatology Digest" afterward. The interview video and the transcript in both English and Chinese are compiled below.

CCHIO International Vision丨Dr. Dorothy Mary Keefe: Current status of cancer prevention and treatment in Australia

By Peter W. PENG 2023.12.11

Editor’s note : Australia faces challenges in the field of cancer prevention and treatment. However, under the challenge, there is also hope. The Australian government is actively taking action to…

Dr. Jessica Seidelman: Implementation of a blood culture algorithm in emergency department patients as a diagnostic stewardship intervention

By Mourabit Halima 2023.12.10

Blood culture is one of the most important tests in the clinical microbiology laboratory. Blood culture is the gold standard for diagnosing bloodstream infection and bacteremia. However, in the United States, blood cultures are still performed even for emergency patients with a low probability of bacteremia, which may result in a large waste of resources. At IDWeek 2023, a study reported the implementation of a blood culture algorithm in emergency department patients as a diagnostic stewardship intervention.

Multiple HIV Research Achievements by Dr. Yaokai Chen’s Team from Chongqing Public Health Medical Center Was Selected for the 2023 IDWeek

By Mourabit Halima 2023.12.10

The IDWeek in the United States is one of the largest infectious disease academic conferences globally, often referred to as the "Oscars" of the infectious disease field. Numerous cutting-edge research findings would be shared and discussed at this highly anticipated academic event. During the recent 2023 IDWeek, Dr. Yaokai Chen's team from Chongqing Public Health Medical Center had four HIV-related research findings selected for the conference. One of these was presented as a Rapid-Fire Poster, while the other three were included in poster presentations.

IDWeek Commentary | Dr. Hongzhou Lu: Can ” Online Celebrity Weight Loss Drugs” Also Be Used for HIV-Infected Individuals?

By Mourabit Halima 2023.12.10

Experiencing weight gain due to medication" is a common concern for many people living with HIV (PLWH). Some antiretroviral therapy (ART) regimens are associated with weight gain and related metabolic complications. In the field of endocrinology, newer antidiabetic medications like glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been used for weight management and have gained popularity. So, are these new weight loss treatments suitable for PLWH experiencing ART-related weight gain? At the 2023 Infectious Diseases Week (IDWeek 2023), two studies on the use of GLP-1 RAs in PLWH and one study of weight control using protease inhibitor switching were presented. Dr. Hongzhou Lu from Shenzhen Third People's Hospital (The Second Hospital Affiliated with the School of Medicine, Southern University of Science and Technology) provides an introduction and commentary on these studies.

IDWEEK Live Interview |Dr. Hardy：Leveraging Stewardship to Promote Narrower-spectrum Antibiotic Use for Low-risk AmpC Enterobacterales

By Mourabit Halima 2023.12.09

AmpC β-lactamases are class C serine β-lactamases that can be produced by a number of Enterobacteriaceae and glucose non-fermenting Gram-negative bacteria. Although AmpC β-lactamases have been associated with the development of third-generation cephalosporin resistance, this risk of AmpC deinhibition is not the same in different enterobacteria. At the recent Infectious Diseases Week 2023 (IDWeek 2023) conference, Professor Megan E. Hardy, a clinical pharmacologist in infectious diseases from the West Virginia University School of Medicine (WVU Medicine) in the United States, orally reported the results of a study titled, "Leveraging Stewardship to Promote Narrower-spectrum Antibiotic Use for Low-risk AmpC Enterobacterales" and shared his fascinating insights in an interview with Infectious Disease Frontier.

2023 China Integrated Oncology Conference Held in Tianjin, Global Oncology Experts Contribute Wisdom to Cancer Prevention and Treatment

By Mourabit Halima 2023.12.08

The 2023 Chinese Congress of Holistic Integrative Oncology(CCHIO 2023) was held in Tianjin, attracting global oncology experts and scholars to contribute to cancer prevention and treatment. Malignant tumors pose a significant threat to public health, and effective cancer control is crucial for the health of the Chinese population.

Professor Chen Yaokai: Factors Affecting the Prognosis of HIV Patients with Talaromyces Marneffei Co-Infection Treated with Amphotericin B Deoxycholate

By Mourabit Halima 2023.12.08

Talaromyces marneffei (TM) is a thermal dimorphic fungus that can cause systemic fungal infections in humans. This fungal infection is common in immunocompromised individuals and is one of the leading causes of death among HIV/AIDS patients in Southeast Asia and South Asia. At the 19th European AIDS Conference (EACS) held from October 18 to 21, 2023, Professor Chen Yaokai and his team from the Chongqing Public Health Medical Treatment Center presented a research report titled "Severe Anemia, Severe Leukopenia, and Severe Thrombocytopenia in HIV-Related Talaromyces Marneffei Infection Induced by Amphotericin B Deoxycholate: A Secondary Analysis of a Prospective Multicenter Cohort Study." This study contributes to global efforts to combat the HIV epidemic and co-infections by presenting findings from China. Below is a summary of their research.

Professor Chen Yaokai: A Systematic Review and Meta-Analysis of Raltegravir Treatment for HIV-Positive Pregnant Women

By Mourabit Halima 2023.12.08

HIV can be transmitted through bodily fluids such as blood, breast milk, semen, and vaginal secretions. Pregnant women who are infected with HIV should receive antiretroviral therapy (ART) as soon as possible to protect their own health and reduce the risk of transmitting HIV to their unborn child. At the recent 19th European AIDS Conference (EACS 2023), Professor Chen Yaokai and his team from the Chongqing Public Health Medical Treatment Center presented a report titled "The Effectiveness of Raltegravir in Virological Suppression of HIV-Positive Pregnant Women at Delivery: A Systematic Review and Meta-Analysis." The study analyzed the effectiveness of Raltegravir treatment for pregnant women with HIV, initiated at different stages of pregnancy, in achieving virological suppression at the time of delivery, and conducted subgroup analyses for treated and untreated pregnant women.