IDweek2023 | Advancements and Challenges in the Pursuit of an HIV Cure: An In-depth Review

IDweek2023 | Advancements and Challenges in the Pursuit of an HIV Cure: An In-depth Review

IDweek2023 Advancements and Challenges in the Pursuit of an HIV Cure: An In-depth Review Human Immunodeficiency Virus (HIV), a global health catastrophe, has demanded an urgent need for comprehensive therapeutic strategies. The search for an HIV cure has been an arduous journey, marked by a series of scientific breakthroughs and disappointments. However, current research proposes several potential strategies that could lead to HIV remission or even a cure. This extensive article aims to provide a thorough understanding of these strategies, focusing on the development of Broadly Neutralizing Antibody (bNAb)-inducing vaccines, the role of inflammasomes in HIV-infected cells, and the distinctive immune and viral features of post-treatment controllers.