Drug-induced liver injury (DILI) is a significant adverse reaction to medications, with severe cases leading to acute liver failure (ALF) and even death. DILI is the most common cause of ALF in Western countries, yet there is still a lack of simple, specific diagnostic indicators and effective treatment methods. The incidence of DILI in China is increasing year by year, related to the variety of clinical drugs, improper medication use, and insufficient awareness. During the recent closure of the 10th "Huaxia Shanghai Liver Disease Forum and Forum on the Diagnosis and Treatment of Liver Failure and its Complications," Dr. Zhengsheng Zou from the Fifth Medical Center of the PLA General Hospital shared insights into the progress of the diagnosis and treatment of drug-induced liver failure, covering its importance, etiology, pathogenic mechanisms, clinical manifestations, treatment strategies, prognosis assessment, and large-scale studies in China.
