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CDL (co-management of diabetes-liver diseases strategy) Literature Review – January 2024, Issue 12
Diabetes and liver disease are prevalent chronic conditions in China, with interconnections in terms of pathogenesis, clinical manifestations, diagnostic and therapeutic targets, making their combined management essential for alleviating the burden of these diseases. In support of the development of diabetes and liver disease co-management initiatives in China, this publication Hepatology Digest, collaborates with the…
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Annual Review |Dr. Haitao Zhao: Molecular Characteristics, Diagnosis and Treatment, and New Drug Progress and Exploration Prospects in Biliary Tract Cancer
Editor’s Note: Although biliary tract cancer (BTC) is relatively rare, it has a higher incidence in the Southeast Asian population, with 50% of patients already in advanced stages at diagnosis and a survival period of less than one year. Its impact cannot be ignored. In 2023, China saw the approval and market launch of the…
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Annual Review | Dr. Guiqiang Wang: Pursuing Clinical Cure for Hepatitis B, Focusing on Advances in New Drug Development
Antiviral therapy is the primary treatment strategy for chronic hepatitis B (CHB), aiming to inhibit HBV replication, alleviate liver cell inflammation and fibrosis, and reduce the risk of liver failure, decompensated cirrhosis, and hepatocellular carcinoma (HCC). However, there is currently no treatment that can completely clear covalently closed circular DNA (cccDNA) in infected liver cells,…
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Anticoagulant Therapy for Acute Pancreatitis-Related Splanchnic Vein Thrombosis
The “Hepatology Digest – Liver Vascular Disease Column” is an academic column initiated by Dr. Qixing Shun from the Department of Gastroenterology, Northern Theater General Hospital, in response to the invitation of the editorial department of “Hepatology Digest”. It regularly collects and organizes research progress in the field of hepatic vascular diseases. Every two weeks…
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Safety and activity of an engineered, liver-tropic adeno-associated virus vector expressing a hyperactive Padua factor IX administered with prophylactic glucocorticoids in patients with haemophilia B: a single-centre, single-arm, phase 1, pilot trial
Hemophilia B is a monogenic inherited bleeding disorder caused by a mutation in the F9 gene, resulting in lifelong excessive bleeding, typically occurring in joints and muscles, leading to arthropathy.…
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Revolutionizing Multiple Myeloma Treatment: FCRL5-Directed CAR-T Cells Enhanced with IL-15 Show Promising Antitumor Activity
In January 2024, a study led by Professor Ting Niu from West China Hospital, Sichuan University was published in the international academic journal ——Signal Transduction And Targeted Therapy (IF=38.104). The title of the study is “Fc receptor-like 5 (FCRL5)-directed CAR-T cells exhibit antitumor activity against multiple myeloma”. This study sheds light on the promising potential…
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Mutation landscape of normal karyotype myelodysplastic syndromes and their prognostic impact
Myelodysplastic syndromes (MDS) encompass a heterogeneous group of hematological disorders characterized by dysplastic changes in the bone marrow, ineffective hematopoiesis, and a risk of progression to acute myeloid leukemia (AML).…
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Low cholesterol levels are associated with increasing risk of plasma cell neoplasm: A UK biobank cohort study
In November 2023, a study led by Professor Ting Niu from West China Hospital, Sichuan University was published in the international academic journal ——Cancer Medicine. The title of the study…
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