• JOH丨GLP-1R/GCGR Dual Agonist Offers New Approach for Treating MASLD

    It is estimated that 25% of adults worldwide are affected by metabolic dysfunction-associated steatotic liver disease (MASLD). MASLD is characterized by at least 5% liver fat content in individuals who do not consume alcohol or consume very little. MASLD represents the liver manifestation of metabolic syndrome and is closely associated with obesity, insulin resistance, and…

  • N-Glycan Markers for Non-Invasive Diagnosis of Liver Fibrosis

    As of 2022, there are 257.5 million people worldwide who are HBsAg positive. Decompensated cirrhosis and hepatocellular carcinoma (HCC) are the leading causes of death among chronic HBV patients. Liver biopsy is the “gold standard” for diagnosing fibrosis stages, but its invasive nature makes many patients reluctant to undergo the procedure. Recently, a study published…

  • AIDS 2024丨In the Era of U=U, Australia’s SVS Rate Among HIV Patients Exceeds 95%

    In recent years, the concept of “U=U” (Undetectable equals Untransmittable) has become widely recognized in the field of HIV prevention. This concept is based on extensive scientific research showing that HIV patients on effective antiretroviral therapy (ART) who achieve and maintain an undetectable viral load (typically defined as less than 20 or 50 copies/mL) have…

  • AIDS Review丨Dr. Yun He: Doxycycline PrEP Reduces STI Incidence in People with HIV

    The 25th International AIDS Conference was held from July 22-26, 2024, in Munich, Germany. At the conference, a randomized controlled trial conducted by the Canadian Centre for Disease Control, the University of British Columbia, and the Canadian HIV Trials Network evaluated the effectiveness of doxycycline pre-exposure prophylaxis (doxyPrEP) in preventing bacterial sexually transmitted infections (STIs)…

  • Meeting Summary on Optimizing Pediatric Tuberculosis Drugs

    Children are the future of humanity and an essential resource for sustainable social development. However, approximately 1.2 million children and adolescents worldwide are threatened by tuberculosis (TB), with drug-resistant TB complicating treatment. To optimize pediatric TB drug treatment strategies, the World Health Organization (WHO) held the second Pediatric Drug Optimization for Tuberculosis (PADO-TB) meeting from…

  • Antimalarial Drugs as Potential Treatment for Polycystic Ovary Syndrome

    Recently, a groundbreaking study published in Science has revealed that the antimalarial drug artemisinin may have potential therapeutic effects on polycystic ovary syndrome (PCOS). PCOS is a complex endocrine disorder primarily affecting women of reproductive age. It is characterized by persistent anovulation, hyperandrogenism, and insulin resistance. Clinically, it manifests as irregular menstrual cycles, enlarged ovaries…

  • AIDS 2024丨Long-Acting Injectable CAB/RPV in Adolescents and Young Adults with HIV: 26-Month Cohort Study Results

    From July 22 to 26, 2024, the 25th International AIDS Conference (AIDS 2024) took place in Munich, Germany, attracting 15,000 professionals and advocates worldwide to discuss the latest advancements and future challenges in HIV prevention and treatment. At the conference, a research team from Children’s National Hospital in the United States, along with several collaborating…

  • Comprehensive Review of Chemotherapy-Induced Anemia Management in China （2）

    Cancer-related anemia (CRA) encompasses anemia that occurs in cancer patients during disease progression or treatment, including non-chemotherapy-related CRA and chemotherapy-induced anemia (CIA). With the increase in chemotherapy treatments, the incidence of anemia is significant, with over 90% of patients not receiving any corrective treatment. To gain a comprehensive understanding of the current practices and perceptions…