• AIDS Exclusive Interview: Latest Advances and Challenges in Long-Acting HIV Prevention Technologies

    At the AIDS 2024 Conference, Dr. Albert Liu from the University of California, San Francisco, delivered a keynote presentation on the latest developments in long-acting HIV prevention technologies. Following his talk, he participated in an exclusive interview with Infectious Diseases Frontier. Dr. Liu highlighted that the field of HIV prevention is currently undergoing exciting transformations.…

  • Spatially resolved transcriptomics: advances and applications

    In January 2023, a review by Professor Tao Cheng  from Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College was published in the international academic journal ——Blood Science . The title of the study is “Spatially resolved transcriptomics: advances and applications”. This review summarizes the interplay between technological innovation and biological discovery continues to push…

  • World’s First Case! Extremely Rare Blood Type Discovered

    Recently, the Blood Transfusion Department at The First Hospital of Handan in Hebei Province identified an extremely rare B subtype blood type. This blood type results from a heterozygous mutation in exon 7 of the ABO allele, specifically c.449A>G, making it even rarer than the well-known “Panda Blood” (Rh-negative blood).

  • Acute Myeloid Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation presenting as pericardial effusion

    In the evolving field of hematology and oncology, addressing acute myeloid leukemia (AML) relapse after allogeneic hematopoietic stem cell transplantation (HSCT) is crucial. A recent study highlighting AML relapse as pericardial effusion marks significant progress in this area. Led by Professor Sizhou Feng from the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of…

  • Sequential Treatment Escalation Improves Survival in Patients with Waldenstrom Macroglobulinemia

    In the dynamic field of hematology and oncology, finding effective treatments for Waldenstrom macroglobulinemia (WM) is crucial. A recent study led by Professor Shuhua Yi from the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College,  has made significant strides in this area. This research analyzed first-…

  • Sequential Infusion of Two Different Chimeric Antigen Receptor T Cells: Induction of a Deep and Durable Remission

    In the dynamic field of hematology and oncology, the development of innovative treatments for challenging conditions such as relapsed or refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) remains a critical priority. In this commentary, the recent phase 2 clinical trial investigating the efficacy of sequential CD19 and CD22 CAR T-cell therapies represents a significant advancement…

  • JOH丨Impact of Pre-Transplant Immunotherapy on Post-Transplant Outcomes in Liver Cancer

    The Journal of Hepatology (JOH) recently published an online systematic review and individual patient data meta-analysis conducted by Cedars-Sinai Medical Center in Los Angeles. The study investigates the impact of using immune checkpoint inhibitors (ICIs) for hepatocellular carcinoma (HCC) before liver transplantation on various key clinical outcomes post-transplantation. The findings reveal that while ICIs treatment…

  • JOH丨Impact of HBV DNA Integration on Diagnosis, Treatment, and Prognosis of Chronic Hepatitis B

    HBV infection is a global public health issue, with its chronic progression leading to severe liver diseases such as chronic hepatitis B (CHB), cirrhosis, and hepatocellular carcinoma (HCC). In recent years, the phenomenon of HBV DNA integrating into the host genome has garnered widespread attention as it unveils new mechanisms of HBV pathogenesis and significantly…