Dr. Dong Hsu: Meeting More Patient Needs in HIV Health Management

Dr. Dong Hsu: Meeting More Patient Needs in HIV Health Management

Implementation Science is a relatively new and increasingly recognized field of research. Its purpose is to translate the possibilities outlined in theory into practical applications in the real world, addressing the challenges of implementing validated intervention measures. At the 2023 APACC conference, Dr. Dong Hsu, from the School of Public Health Management and the Global Health Research Center, Southern Medical University, China, delivered an insightful presentation titled "Implementation of Clinical Practice Guidelines". In our interview, Dr. Dong Hsu further elaborated on the definition and research value of Implementation Science and shared his team's research findings in areas such as HIV screening and health management.
Dr. Taisheng Li: A New Concept in Comprehensive Diagnosis and Treatment in the Post-ART Era of HIV/AIDS

Dr. Taisheng Li: A New Concept in Comprehensive Diagnosis and Treatment in the Post-ART Era of HIV/AIDS

Editor's Note: The 15th National Conference on AIDS and Hepatitis C, hosted by the Chinese Medical Association and its Infectious Diseases Branch, took place in Guangzhou from November 10 to 12, 2023. Dr. Taisheng Li, the conference chair and a renowned figure from Peking Union Medical College Hospital, delivered a captivating presentation titled "A New Concept in Comprehensive Diagnosis and Treatment in the Post-ART Era of HIV/AIDS." In an exclusive interview with Infectious Disease Frontline, he further shared insights on topics including immune reconstitution deficiency in HIV-infected individuals.
Examining LLDT-8’s Potential for Suppressing Immune Activation in SIV/HIV Infection: A Transcriptomic study in Rhesus Macaques

Examining LLDT-8’s Potential for Suppressing Immune Activation in SIV/HIV Infection: A Transcriptomic study in Rhesus Macaques

Human Immunodeficiency Virus (HIV) infection remains a global health challenge, with chronic immune activation playing a pivotal role in disease progression. While antiretroviral therapy (ART) has significantly improved the prognosis by suppressing viral replication, persistent immune activation continues to undermine immune function. LLDT-8, an optimized analog of triptolide, has emerged as a potential immunomodulatory agent, exhibiting promising results in preclinical studies. This article explores in detail the comprehensive transcriptomic analysis conducted to unravel the immunomodulatory effects of LLDT-8 in simian immunodeficiency virus (SIV)-infected rhesus macaques. The study involved a combination of LLDT-8 treatment and ART, employing flow cytometry and RNA-seq analyses to investigate the treatment effects.