Hepatol Int丨Long-term Prognosis of Robotic Liver Resection for Hepatocellular Carcinoma is Safe and Effective

Hepatol Int丨Long-term Prognosis of Robotic Liver Resection for Hepatocellular Carcinoma is Safe and Effective

Primary liver cancer (PLC) is one of the most common cancers worldwide and a leading cause of cancer-related deaths, with hepatocellular carcinoma (HCC) accounting for about 85% of all PLC cases. Despite continuous advancements in medical technology, radical surgical resection of the primary tumor remains a key component of HCC treatment. Robotic liver resection (RLR) is a relatively new technique that combines the advantages of traditional surgery with the precision and flexibility of robotic surgical systems. However, it remains unclear whether RLR is superior to traditional surgery in clinical practice.
Professor Jun Zhu: Rapid Advances in Clinical Trials Usher in a New Era for Lymphoma Diagnosis and Treatment! | 2024 Nanjing Lymphoma Forum

Professor Jun Zhu: Rapid Advances in Clinical Trials Usher in a New Era for Lymphoma Diagnosis and Treatment! | 2024 Nanjing Lymphoma Forum

Amidst the gentle breeze of early summer, the annual "Nanjing Lymphoma Forum" was grandly held in the historic city of Nanjing. This offline event gathered renowned experts in the field of lymphoma from both domestic and international spheres. Through lectures, case discussions, and other formats, the forum facilitated exchanges on the latest achievements and developments in basic and clinical lymphoma research. "Oncology frontier- Hematology frontier" had the privilege of interviewing Professor Jun Zhu, one of the conference chairs and a prominent figure from Peking University Cancer Hospital. He shared the latest research on new drugs such as antibody-drug conjugates (ADCs), bispecific antibodies, and Bruton tyrosine kinase (BTK) inhibitors, emphasizing the crucial role of clinical trials in lymphoma treatment.
EAU24 On-Site Highlights | Professor Wei Zhai: Advances in Urological Tumor Research to Improve Patient Prognosis

EAU24 On-Site Highlights | Professor Wei Zhai: Advances in Urological Tumor Research to Improve Patient Prognosis

The 39th Annual European Association of Urology (EAU24) Congress took place from April 5-8, 2024, in Paris, France, focusing on global urological oncology hotspots and the forefront of Chinese urological research. At the event, "Oncology Frontier" invited Professor Wei Zhai from Renji Hospital, affiliated with Shanghai Jiao Tong University School o,(f Medicine, to share his insights and the latest developments in urological oncology research.
2024 North-South Summit丨Professor Leiping Wang: Is Neoadjuvant Immunotherapy the Future for HR+/HER2- Breast Cancer?

2024 North-South Summit丨Professor Leiping Wang: Is Neoadjuvant Immunotherapy the Future for HR+/HER2- Breast Cancer?

HR+/HER2- is the most common subtype of breast cancer, which is not highly sensitive to neoadjuvant therapy. In 2023, clinical trial results from KEYNOTE-756, CheckMate 7FL, and other studies presented at international conferences showed the potential of neoadjuvant immunotherapy for early-stage HR+/HER2- breast cancer patients. At the 2024 North-South Summit, Professor Leiping Wang from Fudan University Cancer Hospital delivered a report titled "HR+/HER2- Breast Cancer: Entering the Era of Neoadjuvant Immunotherapy?" This article reviews the content of her lecture for readers.
2024 North-South Summit丨Professor Jia Wang: Should Contralateral Prophylactic Mastectomy Be Considered for gBRCA-Mutated Breast Cancer?

2024 North-South Summit丨Professor Jia Wang: Should Contralateral Prophylactic Mastectomy Be Considered for gBRCA-Mutated Breast Cancer?

Among breast cancer patients, 5% to 10% have definite genetic mutations, with gBRCA1/2 mutations accounting for 15% of these cases. Individuals with gBRCA1 mutations have a higher risk of contralateral breast cancer recurrence, making the decision to undergo contralateral prophylactic mastectomy (CPM) a hot topic of discussion. At the 2024 North-South Summit, Professor Jia Wang from The Second Affiliated Hospital of Dalian Medical University delivered a report titled "gBRCA-Mutated Breast Cancer: Should Contralateral Prophylactic Mastectomy Be Considered?" This article reviews the content of the lecture.
Professor Ting Luo: Feasibility of Sequential ADC Treatment in Advanced Breast Cancer: ADC After ADC?丨2024 North-South Meeting

Professor Ting Luo: Feasibility of Sequential ADC Treatment in Advanced Breast Cancer: ADC After ADC?丨2024 North-South Meeting

With the continuous development and market release of new ADC drugs, the treatment landscape for breast cancer patients has changed. For patients with advanced breast cancer, the feasibility of using another ADC drug after the initial ADC treatment has become a common clinical concern. In the "In-depth Inquiry" segment of the 2024 North-South Meeting, Professor Ting Luo from West China Hospital of Sichuan University delivered a report titled "Rescue Treatment for Advanced Breast Cancer: ADC After ADC?". This article reviews the content of her lecture.
EAU24 International Perspective丨Professor Thomas Powles: ADC Combined with Immunotherapy Poised to Reshape Urothelial Carcinoma Treatment

EAU24 International Perspective丨Professor Thomas Powles: ADC Combined with Immunotherapy Poised to Reshape Urothelial Carcinoma Treatment

Urothelial carcinoma is one of the most common malignancies of the urinary system, with high incidence and mortality rates. Despite the efficacy of platinum-based chemotherapy as the standard first-line treatment for advanced urothelial carcinoma, researchers have been relentless in their pursuit of more effective and personalized treatment options. Recent breakthroughs in targeted therapies and immunotherapies have spurred the development of various combination therapies, bringing new hope to patients with advanced urothelial carcinoma. At the recently concluded 39th Annual Congress of the European Association of Urology (EAU24), Oncology Frontier had the privilege of interviewing Professor Thomas Powles from the University of London and Barts Cancer Institute. In this interview, Professor Powles detailed the current status and challenges in the field of advanced urothelial carcinoma, as well as future directions worth exploring.
2024 South-North Forum | Prof. Li Ma: Is Robotic Surgery Necessary for Early-Stage Breast Cancer?

2024 South-North Forum | Prof. Li Ma: Is Robotic Surgery Necessary for Early-Stage Breast Cancer?

The prevalence of robotic surgery in the treatment of early-stage breast cancer is not high, and there is significant debate over its necessity for these patients. At the 2024 South-North Forum, Prof. Li Ma from The Fourth Hospital of Hebei Medical University delivered a presentation on the topic "Is Robotic Surgery Necessary for Early-Stage Breast Cancer?" This article reviews the key points from his lecture.
EAU24 Expert Review | Professor Qiang Wei: Multimodal Treatment of Renal Cancer from a Surgical Perspective

EAU24 Expert Review | Professor Qiang Wei: Multimodal Treatment of Renal Cancer from a Surgical Perspective

The treatment of renal cancer includes surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy. With advancements in treatment technologies, combining the latest modalities for comprehensive treatment of renal cancer is crucial for improving prognosis. The 39th Annual European Association of Urology (EAU24) Congress was held from April 5-8, 2024, in Paris, France, focusing on global urological oncology hotspots and forefront advancements from Chinese urological scholars. "Oncology Frontier" had the opportunity to interview Professor Qiang Wei from West China Hospital, Sichuan University, who shared insights into adjuvant immunotherapy for renal cancer, cytoreductive nephrectomy research, and robot-assisted radical nephrectomy.
Professor Wenbin Qian: Mechanisms of CAR-T Cell Therapy Resistance and Countermeasures | 2024 Nanjing Lymphoma Forum

Professor Wenbin Qian: Mechanisms of CAR-T Cell Therapy Resistance and Countermeasures | 2024 Nanjing Lymphoma Forum

Chimeric Antigen Receptor T-cell Therapy (CAR-T) is a novel cellular immunotherapy technology that has shown excellent efficacy in the treatment of refractory relapsed diffuse large B-cell lymphoma (DLBCL). Despite this, a significant number of patients do not respond to the treatment or experience relapse and progression. How to further improve the efficacy of CAR-T cells is a key focus of future research. At the recently held "2024 Nanjing Lymphoma Forum," Professor Wenbin Qian from The Second Affiliated Hospital of Zhejiang University School of Medicine delivered a brilliant report titled "Mechanisms of CAR-T Resistance Based on DLBCL Pathological Characteristics and Countermeasures." After the conference, "Oncology Frontier - Hematologie Frontier" invited Professor Wenbin Qian for an interview to further discuss this topic.