ESMO ASIA 2024 | Dr. Ken Kato: RATIONALE-305 Confirms the Clinical Benefit of Immunotherapy Plus Chemotherapy as First-Line Treatment for Advanced Gastric Cancer

ESMO ASIA 2024 | Dr. Ken Kato: RATIONALE-305 Confirms the Clinical Benefit of Immunotherapy Plus Chemotherapy as First-Line Treatment for Advanced Gastric Cancer

The global multicenter, randomized, double-blind phase III RATIONALE-305 trial, led by Professor Ruihua Xu as the Global Leading PI, demonstrated that tislelizumab combined with chemotherapy significantly improves overall survival (OS) compared to placebo plus chemotherapy in patients with advanced gastric cancer. This study offers a new first-line treatment option for patients with advanced gastric cancer. At the 2024 European Society for Medical Oncology Asia Congress (ESMO ASIA 2024), the analysis of patient-reported outcomes (PROs) for Asian participants was presented. Oncology Frontier spoke with Dr. Ken Kato from the National Cancer Center Hospital in Japan for his insights.
Annual Review | Challenges and Hopes: Dr. Xianjun Yu Reflects on Pancreatic Cancer Treatment Advances in 2024

Annual Review | Challenges and Hopes: Dr. Xianjun Yu Reflects on Pancreatic Cancer Treatment Advances in 2024

Pancreatic cancer, often called the “king of cancers,” remains a formidable disease with poor patient outcomes. Challenges stem from the complexity and invasiveness of surgical procedures and limited progress in systemic therapies, which are still largely chemotherapy-based. However, 2024 brought new developments in pancreatic minimally invasive surgery and innovative treatment strategies. In an interview with Oncology Frontier, Dr. Xianjun Yu from Fudan University Shanghai Cancer Center shared his perspective on these advancements, highlighting the refinement of surgical techniques and the emergence of precision medicine approaches for pancreatic cancer.