2024 CASH丨Professor Jinghui Zhang:Monitoring clonal hematopoiesis in pediatric patients helps improve long-term prognosis

2024 CASH丨Professor Jinghui Zhang:Monitoring clonal hematopoiesis in pediatric patients helps improve long-term prognosis

Clonal hematopoiesis typically refers to the proliferation of hematopoietic stem cells due to genetic mutations, which is also the basis for various hematologic diseases; monitoring clonal hematopoiesis helps in early detection of hematologic malignancies. At the Fourth China Hematology Development Conference (CASH) held recently, Professor Jinghui Zhang from St. Jude Children's Research Hospital shared a report titled "Treatment-Related Clonal Hematopoiesis in Pediatric Cancer Survivors." Following the conference, "Oncology Frontier - Hematology Frontier" invited Professor Jinghui Zhang to delve deeply into the treatment-related causes, monitoring value, and long-term effects of clonal hematopoiesis.
Unraveling the Complexity of Acute Myeloid Leukemia: Insights from Single-Cell Analysis

Unraveling the Complexity of Acute Myeloid Leukemia: Insights from Single-Cell Analysis

In November 2023, a  study led by Professor XiaoFan Zhu from Chinese Academy of Medical Sciences Blood Disease Hospital (Institute of Hematology, Chinese Academy of Medical Sciences) was published in the international academic journal ——BMC Bioinformatics. The title of the study is "Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia". This study embarks on a pioneering endeavor to decode the continuous hierarchical heterogeneity embedded within AML using single-cell surface antigen analysis.