ILCA 2023 | Dynamic Changes in Circulating Tumor DNA Assist in Guiding and Evaluating Clinical Treatment of Liver Cancer

ILCA 2023 | Dynamic Changes in Circulating Tumor DNA Assist in Guiding and Evaluating Clinical Treatment of Liver Cancer

2024.01.31
 Circulating tumor DNA (ctDNA) refers to free tumor DNA fragments located in peripheral circulation. These free nucleic acids not only provide a comprehensive view of tumor genetics but also indirectly reflect tumor progression, heterogeneity, and invasive ability. They represent a promising non-invasive biomarker in cancer treatment. Dr. Claudia Campani from the University of Paris delivered an oral presentation at the 17th International Liver Cancer Association Annual Meeting (ILCA 2023) (Abstract No.: O-04). The study aimed to assess the dynamic changes in ctDNA levels in hepatocellular carcinoma (HCC) patients across different tumor stages and during anti-cancer treatments. The findings highlighted the significant clinical relevance of monitoring ctDNA levels for HCC patients. Dr. Claudia Campani was honored with the "Young Investigator" award by the ILCA conference.
ILCA 2023 | Liquid Biopsy Technology Based on Methylated SEPT9 Has the Potential to Establish a New Early Diagnosis System for Liver Cancer

ILCA 2023 | Liquid Biopsy Technology Based on Methylated SEPT9 Has the Potential to Establish a New Early Diagnosis System for Liver Cancer

2024.01.31
 Liver cancer is one of the malignant tumors with a high incidence and mortality rate in China. Most patients are clinically diagnosed late, with a high rate of postoperative recurrence and metastasis, which has become a significant factor affecting patient prognosis. There is an urgent need for technology that can effectively detect early liver cancer, monitor treatment effects in real-time, and prevent metastasis. Liquid biopsy technology has attracted attention in recent years as a new detection method. It is non-invasive, sensitive, and dynamic, showing promise in early tumor diagnosis, personalized medication guidance, and treatment monitoring. At the 17th International Liver Cancer Association Annual Meeting (ILCA 2023), Dr. Issei Saeki from School of Medicine of Yamaguchi University,Japan, reported a study (Abstract number: O-11) that assessed the clinical application value of liquid biopsy technology based on the methylated SEPT9 test for early diagnosis of non-viral hepatitis-related hepatocellular carcinoma (N-HCC).