Iron Chelation Therapy in Myelodysplastic Syndrome Mice: A Study on Erythropoiesis and Iron Overload
In December 2023, a study led by Professor XiaoFan Zhu from Chinese Academy of Medical Sciences Blood Disease Hospital (Institute of Hematology, Chinese Academy of Medical Sciences) was published in the international academic journal——Elife. The title of the study is "Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice". The study provides robust evidence for the effectiveness of iron chelation therapy, particularly with deferiprone (DFP), in mitigating anemia and reducing iron overload in a mouse model of myelodysplastic syndrome (MDS).
