Interview with Dr. Luis Paz-Ares: PD-L1 High Expression in Advanced NSCLC, IO Monotherapy vs. IO + Chemotherapy
At the recently concluded 2023 European Lung Cancer Congress (ELCC), Professor Luis Paz-Ares from Madrid University Hospital in Spain presented results from a Phase II trial called CARMEN-LC05 (NCT04524689). The results showed that the antibody-drug conjugate (ADC) targeting CEACAM5, Tusamitamab ravtansineA, in combination with or without pembrolizumab, and chemotherapy, produced responses in CEACAM5-positive non-squamous non-small cell lung cancer (NSCLC) patients in the first-line treatment, and it was well-tolerated.