Antibiotic Therapy Duration

IDweek 2023 Reevaluating the Necessity of Lumbar Punctures in Neonatal Gram-Negative Meningitis Neonatal gram-negative meningitis is a devastating and potentially life-threatening infection that poses significant challenges to clinicians. The management of this condition typically involves prolonged antibiotic therapy, with the duration often determined by the results of lumbar punctures (LPs). However, recent discussions have raised important questions about the necessity of LPs in determining the end of therapy for neonatal gram-negative meningitis. In this article, we will delve into the arguments presented by Dr. Karen M. Puopolo, exploring the potential benefits and drawbacks of LPs in this context, and consider the broader implications of her work.