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Immunogenic Cell Death in Hematological Malignancy Therapy
Hematological malignancies, including leukemia, lymphoma, and multiple myeloma, are characterized by abnormalities in the quantity and quality of blood cells. Immunogenic cell death (ICD) is a unique mechanism that triggers…
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Gene Therapy Using BCMA/CD3 Bispecific Antibody-Encoding Plasmid DNA: A Novel Approach for Treating Multiple Myeloma
Multiple myeloma (MM) remains a significant challenge in the field of hematology, characterized by its incurability and frequent relapses despite advancements in treatment. In the quest for more effective therapies,…
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BSA-AIE Nanoparticles for Immunogenic Cell Death Immunotherapy of Multiple Myeloma
Multiple myeloma (MM) is a hematological cancer characterized by the proliferation of malignant plasma cells in the bone marrow. Despite advancements in MM treatment, relapses and the spread of cancerous…
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Unveiling the Role of BMSCs in NK Cell Exhaustion via the Tim-3/Galectin-9 Pathway in Multiple Myeloma
MM is a hematological neoplasia characterized by the clonal proliferation of aberrant plasma cells, leading to significant health complications. Understanding the mechanisms by which BMSCs contribute to NK cell exhaustion,…
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Examining LLDT-8’s Potential for Suppressing Immune Activation in SIV/HIV Infection: A Transcriptomic study in Rhesus Macaques
Introduction Human Immunodeficiency Virus (HIV) infection remains a global health challenge, with chronic immune activation playing a pivotal role in disease progression. While antiretroviral therapy (ART) has significantly improved the…
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Advancements in Predicting Patient Outcomes: A Multidimensional Approach to COVID-19 with the Omicron Variant
The COVID-19 pandemic, heightened by the emergence of the Omicron variant, has presented substantial challenges in managing patient conditions and predicting outcomes. Researchers at Peking Union Medical College Hospital sought to address this by developing a dynamic prediction model utilizing machine learning techniques. This study aimed to accurately forecast the deterioration or recovery of hospitalized…
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Dr. Taisheng Li: The Evolving “Chinese Approach” to HIV/AIDS Diagnosis and Treatment
Editor’s Note: Since the discovery of the first AIDS patient in China in 1985, an enduring battle, devoid of gunfire, has persisted for nearly forty years. Generation after generation of…
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Dr.Taisheng Li: A New Concept in Comprehensive Diagnosis and Treatment in the Post-ART Era of HIV/AIDS
The 15th National Conference on AIDS and Hepatitis C, hosted by the Chinese Medical Association and its Infectious Diseases Branch, took place in Guangzhou from November 10 to 12, 2023. Dr. Taisheng Li, the conference chair and a renowned figure from Peking Union Medical College Hospital, delivered a captivating presentation titled “A New Concept in Comprehensive Diagnosis…
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