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Quizartinib Plus Chemotherapy in Newly Diagnosed Patients with FLT3-internal-tandem-duplication-positive Acute Myeloid Leukemia: A Phase 3 Trial
Acute myeloid leukemia (AML) is a genetically heterogeneous disease associated with poor clinical outcomes. Mutations in FMS-related receptor tyrosine kinase 3 (FLT3) are common in AML, with FLT3-internal-tandem-duplication (ITD) mutations…
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Current status of diagnosis and treatment of chronic lymphocytic leukemia in China: A nationalmulticenter survey research
Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are mature lymphocyte clonal proliferative tumors that primarily occurs in the middle-aged and elderly population and exhibits specific immunophenotypic characteristics. It is characterized by the abnormal proliferation…
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Efficacy and safety of mitoxantrone hydrochloride liposome injection in treatment of peripheral T-celllymphomas: a multicenter, non-interventional, ambispective cohort, real-world study (MOMENT)
This study is a real-world research with a ambispective cohort (MOMENT study), including clinical data from 198 patients who received mitoxantrone hydrochloride liposome injection as monotherapy or combination therapy at…
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Shanghai Institute of Hematology’s Team Led by Academician SaijuanChenand Chief Physician Jianqing Mi Unveils Temporal Characteristics of Cytokine Release and Molecular Mechanisms of CAR-T Re-expansion in Cell Immunotherapy
In January 2024, the team led by Academician Saijuan Chen and Chief Physician Jianqing Mi at the Shanghai Institute of Hematology published a research paper in the journal “Nature Communications.” The…
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Hematologica | Team Led by Jianxiang Wang Publishes Results of the Largest Domestic Prospective Cohort Study on Treating Adult Ph-negative ALL with Pediatric-inspired Regimen
Acute Lymphoblastic Leukemia (ALL) is a malignant hematologic tumor characterized by the clonal proliferation of immature lymphocytes in the bone marrow, peripheral blood, and extramedullary tissues. ALL predominantly affects children…
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Clin Cancer Res丨Gang An/Lugui Qiu Team First in China to Confirm Mass Spectrometry Technology for Minimally Invasive Monitoring of MRD in MM Patients Through Targeted Tracking of Serum M-Protein
The study incorporated 56 newly diagnosed MM patients from the national hematologic disease longitudinal cohort-multiple myeloma sub-cohort. By conducting easyM MS testing (a mass spectrometry-based protein analysis method) on the…
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Professor Cai-Cun Zhou: KRAS G12D Inhibitor HRS-4642 Shows Encouraging Activity in Late-Stage Solid Tumors with KRAS G12D Mutation
The 2023 European Society for Medical Oncology (ESMO) Annual Meeting took place in Madrid, Spain, from October 20th to 24th. The Tumor Insight team delved into the front lines, capturing international advancements and witnessing China’s contributions to the field of oncology on the global stage. Professor Cai-Cun Zhou from Tongji University Affiliated Shanghai Pulmonary Hospital…
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ESMO Big Shot Interview | Professor Xu Ruihua: Oncology in China Is Thriving, with a Record Number of Selected Papers
The 2023 European Society for Medical Oncology (ESMO) Annual Congress was held in Madrid, Spain from October 20th to 24th. The Oncology Horizon team went deep into the front lines, capturing international advancements and witnessing the progress of cancer research in China on the global stage. Professor Xu Ruihua from Sun Yat-sen University Cancer Center…
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