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EAU24 International Perspective丨Professor Thomas Powles: ADC Combined with Immunotherapy Poised to Reshape Urothelial Carcinoma Treatment
Urothelial carcinoma is one of the most common malignancies of the urinary system, with high incidence and mortality rates. Despite the efficacy of platinum-based chemotherapy as the standard first-line treatment for advanced urothelial carcinoma, researchers have been relentless in their pursuit of more effective and personalized treatment options. Recent breakthroughs in targeted therapies and immunotherapies…
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2024 South-North Forum | Prof. Li Ma: Is Robotic Surgery Necessary for Early-Stage Breast Cancer?
The prevalence of robotic surgery in the treatment of early-stage breast cancer is not high, and there is significant debate over its necessity for these patients. At the 2024 South-North Forum, Prof. Li Ma from The Fourth Hospital of Hebei Medical University delivered a presentation on the topic “Is Robotic Surgery Necessary for Early-Stage Breast…
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EAU24 Expert Review | Professor Qiang Wei: Multimodal Treatment of Renal Cancer from a Surgical Perspective
The treatment of renal cancer includes surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy. With advancements in treatment technologies, combining the latest modalities for comprehensive treatment of renal cancer is crucial for improving prognosis. The 39th Annual European Association of Urology (EAU24) Congress was held from April 5-8, 2024, in Paris, France, focusing on global urological…
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Professor Wenbin Qian: Mechanisms of CAR-T Cell Therapy Resistance and Countermeasures | 2024 Nanjing Lymphoma Forum
Chimeric Antigen Receptor T-cell Therapy (CAR-T) is a novel cellular immunotherapy technology that has shown excellent efficacy in the treatment of refractory relapsed diffuse large B-cell lymphoma (DLBCL). Despite this, a significant number of patients do not respond to the treatment or experience relapse and progression. How to further improve the efficacy of CAR-T cells…
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Effectiveness and Safety of Direct Oral Anticoagulants in the Treatment of Visceral Vein Thrombosis
The “Hepatology Digest – Liver Vascular Diseases” column is a scholarly column co-initiated by Dr. Xingshun Qi from the Department of Gastroenterology at the General Hospital of Northern Theater Command, at the invitation of the editorial board of Hepatology Digest. This column regularly collects and summarizes research progress in the field of liver vascular diseases,…
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Hepatol Int | 24-Hour Comprehensive Lifestyle Interventions Help Prevent and Control MAFLD
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common liver disease worldwide, with recent data showing prevalence rates of up to 39% in adults and 20% in children. MAFLD is characterized by overweight or obesity, type 2 diabetes, and/or metabolically dysregulated hepatic steatosis and can coexist with various hepatic and cardiovascular metabolic diseases.
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Prof. Pengfei Qiu: Do Breast Cancer Patients with cN1 Who Downstage to ycN0 after Neoadjuvant Therapy and Have Limited SLNB Metastasis Need ALND?
The axillary lymph node burden after neoadjuvant therapy is closely related to prognosis. Unlike the assessment in initial surgery patients, residual tumor cells after neoadjuvant therapy are considered resistant cells. Thus, can limited sentinel lymph node biopsy (SLNB) metastasis after neoadjuvant therapy exempt patients from axillary lymph node dissection (ALND)? At the 2024 South-North Forum,…
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Professor Yuqian Sun: Advances in Salvage Treatment for Primary Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation Graft Failure
Graft failure is a rare but fatal complication following haploidentical allogeneic hematopoietic stem cell transplantation. A second transplant is almost the only salvage measure for transplant failure. However, outcomes from second transplants have generally been poor, as reported in previous literature. The 50th European Society for Blood and Marrow Transplantation (EBMT) annual meeting was held…