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ASCO GI 2025 | Dr. Xiufeng Liu’s In-Depth Analysis of CheckMate 9DW and CARES-310 Study Updates
The landscape of systemic therapy for hepatocellular carcinoma (HCC) has undergone a major transformation, shifting from single-agent targeted or immunotherapies to dual immune checkpoint inhibitors and immune-targeted combination regimens. The 2025 ASCO Gastrointestinal Cancers Symposium (ASCO GI), held on January 23, 2025, highlighted two pivotal studies—CheckMate 9DW and CARES-310—focusing on dual immunotherapy strategies for previously…
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Dr. Xiangrui Meng: “VEGF-TKI + PD-1 Inhibitor + Chemotherapy” as a Potential New Treatment Option for PD-L1-Negative Advanced Gastric Cancer
In recent years, the emergence and breakthrough progress of multiple targeted and immunotherapy drugs, along with their combination regimens, have brought significant transformation to the systemic treatment of esophageal and gastric cancer. The field has evolved from monotherapy with targeted or immune agents to an era of dual or multi-immunotherapy combinations.
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New Research on PORT-77 for Erythropoietic Protoporphyria (EPP) Presented at ASH 2024
Phototoxicity and liver damage are significant challenges for individuals with Erythropoietic Protoporphyria (EPP), a rare genetic disorder caused by the accumulation of protoporphyrin IX (PPIX). At ASH 2024, Bhavik Shah…
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ASCO GI 2025 | Professor Yanhong Deng’s Team Presents Two Colorectal Cancer Studies at ASCO GI 2025 – Expert Interpretation by Dr. Xiaoshuang Lü
To provide a deeper understanding of these important findings, Oncology Frontier meticulously compiled and analyzed the key insights from these studies. Additionally, Dr. Xiaoshuang Lü, a postdoctoral researcher from Professor…
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Can Axillary Ultrasound Reliably Predict Nodal Status After Neoadjuvant Chemotherapy? Insights from the AXSANA Trial
At #SABCS24, Steffi Hartmann presented findings from the AXSANA registry trial (NCT04373655), the largest prospective study evaluating the diagnostic performance of axillary ultrasound (AUS) in initially node-positive breast cancer patients…
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ASCO GI 2025 | Dr. Ying Yuan: BBCAPX Regimen as a Potential Immunotherapy Breakthrough for RAS-Mutant MSS mCRC with Liver Metastases
The 2025 ASCO Gastrointestinal Cancers Symposium (ASCO GI) commenced in San Francisco on January 23, 2025. During the conference, Dr. Ying Yuan from The Second Affiliated Hospital of Zhejiang University School of Medicine presented the latest survival data and subgroup analysis from the BBCAPX study. Oncology Frontier had the privilege of discussing the updated findings…
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Investigating the Thrombotic Risks of a Highly Prevalent GRK5 Variant
A recent study presented at hashtag#ASH2024 explores the mechanistic insights and clinical implications of a widely prevalent GRK5 variant affecting platelet function. featuring Yanki Yarman, this research highlights how the…
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Can a Ketogenic Diet Enhance CAR T-Cell Therapy?
New findings presented at ASH2024 suggest that a ketogenic diet and its key metabolite, β-hydroxybutyrate (BHB), may improve CAR T-cell antitumor function. In preclinical models, BHB fueled CAR T-cell metabolism,…
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