The impact of long-term toxicity management on patient quality of life is increasingly being recognized in breast cancer treatment. At the recently held 19th St. Gallen Breast Cancer Conference (SGBCC 2025), Dr. Cynthia Villarreal-Garza, Director of Clinic Oncology at the Breast Cancer Center, TecSalud,delivered a presentation titled “Ensuring Long-term Healthy Survival of Breast Cancer Patients.” She pointed out that young breast cancer patients, due to the high intensity and long duration of their treatment, face a number of unique toxicity issues that not only affect their physical health but also have a profound impact on their psychological well-being, social functioning, and overall quality of life. To monitor and intervene in these long-term toxicities, Professor Villarreal-Garza proposed the application of “evidence-based approaches for healthy living” and the use of remote monitoring applications to effectively manage toxicities and improve patient quality of life.