International Hepatology

New research evaluates the effectiveness of abbreviated MRI (AMRI) compared to ultrasound in detecting early-stage hepatocellular carcinoma (HCC). Findings suggest that AMRI significantly outperforms ultrasound in sensitivity and specificity, particularly…

Liver cancer is the third leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (HCC) accounting for nearly 90% of primary liver cancers. The newly updated EASL Clinical Practice Guidelines…

A recent study published in Hepatology explores the role of SUMOylation in cholangiocarcinoma (CCA) and its potential as a therapeutic target. The research analyzed tumors from multiple patient cohorts and…

A recent phase IIb randomized trial, published in the Journal of Hepatology, evaluated Icosabutate, an oral FFAR1/FFAR4 agonist, in patients with biopsy-confirmed MASH and fibrosis (F1-F3). While the primary endpoint…

New research in JHEP Reports explores how Salsalate, a rheumatoid arthritis therapy, may enhance the effectiveness of Lenvatinib in treating MASH-driven hepatocellular carcinoma (HCC). By stimulating AMPK, enhancing fatty acid…

The Journal of Clinical Oncology features an important discussion led by Neil Newman MD MS, Colin Court, MD, PhD, and Alexander Parikh, MD, MPH on the best locoregional treatment strategies…

Alcohol use disorder remains a leading but preventable cause of morbidity and mortality worldwide, with profound implications for chronic liver disease. Yet, despite its significant burden, clinicians often face challenges…