Hematology Frontier

In this era of information explosion, how can one quickly access the latest developments in the field? Here, we select the latest literature in the field every month, focusing on hot topics, comprehensively interpreting new advances in hematologic diseases, and helping you stay at the forefront of the disease field. Let's track the latest trends together, gain insights into research trends, and explore the boundless possibilities in the world of hematology! Stay tuned every month for the latest updates!

The "News Express" column serves as a bridge between cutting-edge research and clinical practice, enabling hematology enthusiasts and professionals to swiftly capture industry trends, ignite innovative thinking, and broaden their professional perspectives. Hematology Frontier carefully selects the latest hematological research findings from top global journals. Each article is a brilliant spark of science and clinical practice, delivering the latest advancements in hematology directly to you. Let knowledge know no boundaries, and let exploration never cease. We invite you to follow the column and join global hematology experts on a journey of scientific discovery! This special issue compiles notable leukemia research from the past six months in Blood Reviews. We invite you to explore these highlights.

The "11th Sino-French Hematology Summit of the Chinese Medical Doctor Association," organized by the Chinese Medical Doctor Association, the Hematology Branch of the Chinese Medical Doctor Association, and the French Hematology Association, and hosted by the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (Institute of Hematology, Chinese Academy of Medical Sciences) and the National Clinical Research Center for Hematological Diseases—Peking University Hematology Institute, with the support of the French Bo Xiao Foundation under the French Fund General Assembly, is scheduled to be held in Tianjin from September 13 to 15, 2024. The conference theme focuses on "New Advances in the Treatment of Hematological Malignancies," delving into the latest clinical diagnosis and treatment progress, current hot topics, and core challenges in clinical practice related to the hematopoietic system. This conference sincerely invites authoritative experts in the field of hematology from both international and domestic circles to share their insights and experiences. It is planned to invite 150 hematologists from across the country to participate and exchange academic experiences. We warmly welcome clinicians on the front line of hematology to actively participate in the meeting and jointly promote progress in the field of hematological malignancy treatment.

The "News Express" column serves as a bridge between cutting-edge research and clinical practice, enabling hematology enthusiasts and professionals to swiftly capture industry dynamics, ignite innovative thinking, and broaden their professional perspectives. Hematology Frontier carefully selects the latest hematological research findings from top global journals. Each article is a brilliant spark of science and clinical practice, delivering the latest advancements in hematology directly to you. Let knowledge know no boundaries, and let exploration never cease. We invite you to follow the column and join global hematology experts on a journey of scientific discovery! This issue features a review article from Pediatric Blood & Cancer on the role of Vinca alkaloids, a must-read.

The 8th Hematology Academic Conference, organized by the Chinese Society of Clinical Oncology (CSCO), CSCO Leukemia Expert Committee, and CSCO Lymphoma Expert Committee, and co-hosted by Harbin Institute of Hematology and Oncology and Peking University Cancer Hospital, was grandly held in Harbin from July 26 to 28, 2024. On this occasion, "Oncology Frontier - Hematology Frontier" invited Dr. Jian Hou from Renji Hospital of Shanghai JiaoTong University School of Medicine, to share insights on the current status, challenges, and future treatment modes of multiple myeloma (MM).

Mantle cell lymphoma (MCL) is an aggressive lymphoma with high malignancy and poor treatment outcomes, especially for elderly patients or those in poor health. Optimizing treatment regimens for these patient groups is crucial. At the recent 29th European Hematology Association (EHA) annual meeting, Dr. Michael Wang from University of Texas MD Anderson, Houston, USA presented the latest results from the phase 3, double-blind, placebo-controlled ECHO trial (LB3439), which evaluated the efficacy of acalabrutinib combined with bendamustine and rituximab in treatment-naïve MCL patients. "Oncology Frontier - Hematology Frontier" interviewed Professor Wang to interpret these groundbreaking findings.

The 29th European Hematology Association (EHA) Annual Meeting was successfully held in Madrid, Spain, from June 13 to 16, 2024. As the largest international conference in the field of hematology in Europe, it annually attracts experts and scholars from around the world to share and discuss innovative ideas and the latest scientific and clinical research results in hematology. At this year's conference, several studies from Dr. He Huang's team at The First Affiliated Hospital, Zhejiang University School of Medicine were selected for poster presentations. These studies, covering both basic and clinical research, provide new perspectives and theoretical foundations for the treatment of hematological diseases. This article introduces five of these studies, including the impact of telomere length on transplant prognosis, the role of lactate in acute graft-versus-host disease, the regulatory mechanisms of hematopoietic endothelial cell (HECs) generation, breakthroughs in CD7 CAR-T therapy for T-cell malignancies, and the prospects of XPO1 inhibitors in the treatment of Burkitt lymphoma.

The European Hematology Association (EHA) annual meeting, one of the most influential international academic conferences in the field of hematology, gathers numerous experts and scholars worldwide every year. The aim is to share and deeply discuss innovative ideas and the latest scientific and clinical research advancements in hematology, thereby promoting continuous progress in the field. This year’s conference unveiled the latest results from studies on the use of the erythroid maturation agent luspatercept in the treatment of lower-risk myelodysplastic syndromes (LR-MDS), demonstrating promising therapeutic potential. Oncology Frontier - Hematology Frontier invited Dr. Chungkang Chang , Director of the Hematology Department at Shanghai Sixth People’s Hospital Affiliated to Shanghai JiaoTong University and Deputy Director of the Shanghai Blood Research Institute, to provide an in-depth analysis of the field's current status and research content, aiming to offer valuable references for clinical practice.

In the field of lymphoma diagnosis and treatment, traditional methods such as tissue biopsy, while valuable, are increasingly showing limitations due to their invasive nature, inconvenience in repeated sampling, and inability to fully reflect tumor heterogeneity. Liquid biopsy, as an emerging non-invasive testing technology, is demonstrating great potential in the diagnosis and treatment of lymphoma. At the recently held "The 8th Hematologic Oncology Academic Conference of the Chinese Society of Clinical Oncology (CSCO)", Dr. Davide Rossi from the Swiss Institute for Experimental Cancer Research in Bellinzona shared exciting insights on "The Role of Liquid Biopsy (ctDNA) in the Diagnosis and Treatment of Malignant Lymphomas". "Hematology Frontier" specially invited Dr. Davide Rossi for an interview at the venue to further delve into this topic.

In order to further improve the diagnostic and treatment level of leukemia and lymphoma in China, "The 8th Hematologic Oncology Academic Conference of CSCO," co-hosted by the Chinese Society of Clinical Oncology (CSCO), the Leukemia Expert Committee of CSCO, and the Lymphoma Expert Committee, and co-organized by the Harbin Hematological Tumor Research Institute and Peking University Cancer Hospital, was grandly held in Harbin from July 26 to 28. The conference aims to build an important platform for in-depth learning and extensive exchange for many experts and scholars in the field of hematologic oncology. On the occasion of the conference, "Hematology Frontier" specially invited Dr. Owen O'Connor, Chairman of the American Lymphoma Alliance and the University of Virginia Cancer Center, to conduct in-depth academic discussions and share exciting insights around the cutting-edge progress of Peripheral T-Cell Lymphoma (PTCL).