Hematology Frontier

The 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) Congress was held in Bangkok, Thailand, from June 22 to June 26, 2024. As the most influential international event in the field of thrombosis and haemostasis, the ISTH Congress attracts thousands of top experts and scholars from around the world each year, with its profound academic impact and rich academic content. "Oncology Frontier - Hematology Frontier" is dedicated to synchronously delivering cutting-edge academic information. Here, we highlight outstanding research findings to provide academic reference information for the field of hematological diseases.

From July 5th to 7th, the highly anticipated 2024 Annual Progress Seminar in Clinical Oncology in China (BOC) and Best of ASCO 2024 China were grandly held in Guangzhou. Based on the actual situation of cancer incidence in China, the conference specially invited authoritative experts in the field of oncology and carefully selected outstanding papers from the 2024 ASCO conference for comprehensive and in-depth interpretation. During the conference, "Oncology Frontier - Hematology Frontier" conducted an exclusive interview with Professor Tiejun Gong from the Harbin Institute of Hematology and Oncology. He shared his profound insights and unique academic perspectives on major studies presented at ASCO this year, the progress of the novel CD3 x CD19 IgG4 bispecific antibody CN201, and the overall status and future prospects of hematologic oncology treatment in China.

Aggressive lymphomas progress rapidly and are prone to relapse, with existing treatments still failing to achieve a satisfactory cure rate. Particularly for high-risk patient groups, the demand for precise and efficient treatments is more urgent. The 12th Annual Meeting of the Society for Hematologic Oncology (SOHO 2024) was held in Houston, USA, from September 4th to 7th, 2024, attracting top experts in the field of hematologic malignancies from around the world to exchange the latest research findings and discuss new strategies for treatment. During the conference, "Hematology Frontier" had the honor to interview Dr. Astrid Pavlovsk from the Pavlovsky Center. She provided an in-depth analysis of the efficacy, safety, and current status of new therapies in the treatment of aggressive lymphomas, with a special focus on key issues such as patient individual differences, offering insights for clinical practice.

The 29th European Hematology Association (EHA) Annual Meeting was grandly held in Madrid, Spain, from June 13-16, 2024. As the largest international conference in the field of hematology in Europe, it attracts experts and scholars from around the world every year to share and discuss innovative ideas and the latest scientific and clinical research findings in hematology. At this year's conference, the latest classification standards and clinical research outcomes for MDS received widespread attention. "Oncology Frontier - Hematology Frontier" invited Professor Hongyan Tong from The First Affiliated Hospital, Zhejiang University School of Medicine to provide an in-depth interpretation of the key updates in the latest WHO MDS classification standards and share her team's groundbreaking research achievements in MDS, particularly in the MDS-f subtype.

The 29th Annual Congress of the European Hematology Association (EHA) was grandly held in Madrid, Spain, from June 13 to 16, 2024. As the largest international conference in the field of hematology in Europe, it attracts experts and scholars from all over the world every year to share and discuss innovative ideas and the latest scientific and clinical research findings in hematology. At this year's conference, a study by Dr. Yang Liang from Sun Yat-sen University Cancer Center was selected for poster presentation, exploring how FLT3-ITD promotes immune escape in AML cells by up-regulating CD47 expression and reducing the phagocytic ability of macrophages. To provide insight into these research findings, "Oncology Frontier-Hematology Frontier" invited Dr. Yang Liang to give us a brief introduction to the study.

On July 5th, the 17th Beijing Hematology Academic Annual Meeting, hosted by the Beijing Medical Association Hematology Branch, concluded successfully in Beijing. This year's meeting featured innovative and unique formats and rich content, providing a platform for participants to share cutting-edge advancements and experiences. It also showcased the original research achievements in the field of hematology in Beijing. "Oncology Frontier - Hematology Frontier" invited Professor Qian Jiang, the current chair of the Beijing Medical Association Hematology Branch, the main organizer of this conference, and a professor at Peking University People's Hospital, to share the highlights and unique aspects of the meeting and to discuss its far-reaching impacts on the future.

At the 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) conference, the research team led by Dr. Xiaoyu Zhu and Dr. Aijie Huang from The First Affiliated Hospital of the University of Science and Technology of China (Anhui Provincial Hospital) garnered significant attention. Their study on the efficacy and safety of avatrombopag for treating thrombocytopenia following cord blood transplantation (UCBT) was selected for oral presentation (OC33.3), with Dr. Huang delivering the report. This study not only showcases the exceptional capabilities of Chinese research teams in hematology but also contributes valuable insights to the global hematology community. "Oncology Frontier - Hematology Frontier" had an exclusive interview with Dr. Aijie Huang to delve deeper into the research and discuss future plans in the field of UCBT.

The "News Express" column aims to bridge the gap between cutting-edge research and clinical practice, allowing every hematology enthusiast and professional to quickly capture industry trends, spark innovative thinking, and broaden professional horizons. Hematology Frontier carefully selects the latest hematology research findings from top global journals, delivering every brilliant spark of science and clinical practice to you. We invite you to follow this column and join global hematology experts on the journey of scientific exploration!

Angioimmunoblastic T-cell lymphoma (AITL), as a major subtype of peripheral T-cell lymphoma (PTCL), poses significant challenges for clinicians due to its complex pathological features, variable clinical presentation, and poor prognosis. In recent years, with advances in medical research, novel diagnostic techniques and treatment methods for nTFHL have emerged, leading to new breakthroughs in diagnosis and therapy. However, patient outcomes remain bleak, underscoring the urgent need for further basic and clinical research to guide clinical practice and improve prognosis. Recently, Dr. Jianyong Li from Jiangsu Province Hospital provided a detailed overview of the latest research progress in nodal T-follicular helper cell lymphoma (nTFHL). Hematology Frontier has compiled these insights for our readers.

In the realm of cellular therapy, CAR-NK technology is spearheading a new wave of treatment possibilities. Given the current state of cellular therapy in China, advancing technologies like CAR-NK has become crucial. At the 12th Lu Daopei Hematology Forum, Hematology Frontier had the privilege of inviting Dr. Wenbin Qian from The Second Affiliated Hospital Zhejiang University School of Medicine to provide an in-depth analysis of the benefits and challenges of CAR-NK therapy, explore future research directions, and discuss new chapters in cellular therapy.