Mourabit Halima, Author at MediaMedic

Dr. Sujun Zheng: Advances in the Diagnosis and Treatment of Inactive HBsAg Carriers

By Mourabit Halima 2024.08.28

According to estimates from the Polaris Observatory, the prevalence of inactive hepatitis B surface antigen (HBsAg) carriers in the general population in China was 6.1% in 2016, with approximately 86 million people chronically infected with HBV. This suggests that around 36.08% of these individuals are inactive HBsAg carriers (IHC), equating to about 30.96 million people. The definitions and treatment recommendations for IHC vary across national or regional chronic hepatitis B (CHB) guidelines. As research into the natural history of CHB deepens and antiviral treatment strategies evolve, the management of HBV infection is gradually changing. At a recent Beijing Hepatology Academic Annual Meeting, Dr. Sujun Zheng from Beijing You An Hospital, Capital Medical University, presented an insightful report on "Advances in the Diagnosis and Treatment of Inactive HBsAg Carriers." Here, we summarize the key points.

SIFIC: Leading with Wisdom, Embracing Openness and Innovation

By Mourabit Halima 2024.08.28

Recently, the 20th Shanghai International Forum for Infection Control (SIFIC) and the 8th Oriental Forum on Complex Infectious Diseases (OFCID), along with the Annual Academic Meeting of the Global Chinese Clinical Microbiology and Infectious Diseases Society, were successfully held in Shanghai. Infectious Diseases Frontier had the privilege of interviewing several administrators of the SIFIC forum at the event. They shared the development journey of SIFIC and their personal growth stories from different perspectives. Through these real experiences, we gained insight into how SIFIC, with an open attitude and innovative spirit, is leading the development of infection control in China, while also witnessing how each participant has achieved personal growth and value enhancement in this process.

Dr. Davide Rossi: The Role of Liquid Biopsy (ctDNA) in the Diagnosis and Treatment of Malignant Lymphoma

By Mourabit Halima 2024.08.27

In the field of lymphoma diagnosis and treatment, traditional methods such as tissue biopsy, while valuable, are increasingly showing limitations due to their invasive nature, inconvenience in repeated sampling, and inability to fully reflect tumor heterogeneity. Liquid biopsy, as an emerging non-invasive testing technology, is demonstrating great potential in the diagnosis and treatment of lymphoma. At the recently held "The 8th Hematologic Oncology Academic Conference of the Chinese Society of Clinical Oncology (CSCO)", Dr. Davide Rossi from the Swiss Institute for Experimental Cancer Research in Bellinzona shared exciting insights on "The Role of Liquid Biopsy (ctDNA) in the Diagnosis and Treatment of Malignant Lymphomas". "Hematology Frontier" specially invited Dr. Davide Rossi for an interview at the venue to further delve into this topic.

Dr. Owen O’Connor: The Vessel of Hope for Peripheral T-Cell Lymphoma Braves the Storm and Forges Ahead Fearlessly | The 8th Hematologic Oncology

By Mourabit Halima 2024.08.27

In order to further improve the diagnostic and treatment level of leukemia and lymphoma in China, "The 8th Hematologic Oncology Academic Conference of CSCO," co-hosted by the Chinese Society of Clinical Oncology (CSCO), the Leukemia Expert Committee of CSCO, and the Lymphoma Expert Committee, and co-organized by the Harbin Hematological Tumor Research Institute and Peking University Cancer Hospital, was grandly held in Harbin from July 26 to 28. The conference aims to build an important platform for in-depth learning and extensive exchange for many experts and scholars in the field of hematologic oncology. On the occasion of the conference, "Hematology Frontier" specially invited Dr. Owen O'Connor, Chairman of the American Lymphoma Alliance and the University of Virginia Cancer Center, to conduct in-depth academic discussions and share exciting insights around the cutting-edge progress of Peripheral T-Cell Lymphoma (PTCL).

EHA Global Perspectives | Dr. Edward Laane: Advancing Breakthroughs in MM Treatment and PRO Standardization

By Mourabit Halima 2024.08.27

Multiple myeloma (MM) has long been a focus of hematology research due to its complex nature and the challenges it presents in treatment. As treatment methods continue to advance and new drugs emerge, patient survival rates and quality of life are receiving unprecedented attention. In this context, the accurate measurement of patient-reported outcomes (PROs) becomes increasingly important. It not only helps us gain a deeper understanding of patients’ real experiences but also provides guidance for developing more precise treatment strategies. At the 29th Annual Congress of the European Hematology Association (EHA 2024), held from June 13-16, Dr. Edward Laane from Tartu University in Estonia presented groundbreaking research that not only made significant strides in MM treatment but also offered new perspectives and methods for the standardization of PRO measurements. Hematology Frontier invited Dr. Edward Laane to share his team’s research findings and his special insights from the conference.

Dr. Dong Ji: Exploring Liver Fibrosis Reversal and Personalized Treatment

By Mourabit Halima 2024.08.26

The liver is a powerful organ with complex physiological structures and functions. Liver fibrosis is a dynamic pathological process associated with various chronic liver diseases, ultimately leading to cirrhosis. In cirrhosis, the liver not only becomes harder but also shrinks in size, with imaging showing changes in the liver's appearance accompanied by alterations in hepatic hemodynamics. Recently, at the 10th Beijing Hepatology Academic Annual Conference in 2024, Hepatology Digest invited Dr. Dong Ji from the Fifth Medical Center of the Chinese PLA General Hospital to discuss the latest insights and strategies on liver fibrosis reversal. The interview has been compiled into this article for readers to reference.

Dr. Hui Wang: PURPOSE 1 Study Reveals Outstanding Efficacy of Long-Acting Injectable Lenacapavir in Preventing HIV Infection in Women

By Mourabit Halima 2024.08.26

On July 24th, during the highly anticipated Co-Chairs' Choice session at the 25th International AIDS Conference in Munich, Germany, the PURPOSE 1 study was unveiled, highlighting a significant breakthrough in HIV prevention. The study demonstrated the exceptional efficacy of the long-acting injectable drug Lenacapavir in preventing HIV infection among women. The study was simultaneously published online in The New England Journal of Medicine. Conducted in South Africa and Uganda, this double-blind, randomized controlled trial compared different prevention strategies and found that biannual injections of Lenacapavir effectively blocked HIV infection, resulting in zero cases of infection. The efficacy of Lenacapavir far surpassed that of daily oral F/TAF and F/TDF. The study not only confirmed Lenacapavir's high effectiveness but also revealed its potential to improve patient adherence, offering a new solution to one of the major challenges in HIV prevention. With the widespread application of Lenacapavir, global HIV prevention strategies may be poised for significant change. Infectious Diseases Frontier invited Dr. Hui Wang from the Second Affiliated Hospital of Southern University of Science and Technology (Shenzhen Third People's Hospital) to provide an in-depth commentary and analysis of this study.

SIFIC 2024 | Dr. Fan Wu: Challenges and Control of Candida auris and Babesiosis

By Mourabit Halima 2024.08.26

The 20th Shanghai International Forum for Infection Control (SIFIC) and the 8th Oriental Forum on Complex Infectious Diseases (OFCID), jointly held with the Global Chinese Society of Clinical Microbiology and Infectious Diseases (GCSCMID) Annual Meeting, successfully took place at the Shanghai International Convention Center from July 25-27, 2024. During the event, Dr. Fan Wu from Medical School of columbia University delivered in-depth presentations on "Individual Diagnosis and Treatment of Candida auris Infections and Population-Level Prevention and Control" and "Mother-to-Child Transmission of Babesiosis - A Potentially Dangerous Blood Parasitic Disease." In an interview with "Infectious Diseases Frontier," Dr. Wu further elaborated on the global threat posed by Candida auris and the challenges in controlling Babesiosis, providing new insights and directions for the field of infection control.

News Express | Belzutifan, an Oral HIF-2α Inhibitor, for Treating VHL-Associated Congenital Polycythemia

By Mourabit Halima 2024.08.26

The "News Express" column aims to bridge the gap between cutting-edge research and clinical practice, enabling hematology enthusiasts and professionals to quickly grasp industry trends, spark innovative thinking, and broaden their professional horizons. Hematology News carefully curates the latest hematological research findings from top global journals. Each selected article represents a fusion of science and clinical practice, delivering the essence of hematology's advancements straight to you. Let knowledge transcend boundaries, and exploration never cease. We invite you to follow the column and join global hematology elites on a journey of scientific discovery! This issue features a case report from Haematologica on VHL-associated congenital polycythemia (CP).

Dr. Bing Xu: Understanding and Conquering IVLBCL—Progress in Diagnosis and Treatment | 2024 Northern Hematology and Oncology Immunotherapy Conference

By Mourabit Halima 2024.08.26

Intravascular large B-cell lymphoma (IVLBCL) is a rare form of non-Hodgkin lymphoma with atypical clinical presentations, leading to high rates of misdiagnosis and missed diagnosis in clinical practice. There is an urgent need to improve the current status of diagnosis and treatment. Recently, the "2024 Northern Hematology and Oncology Immunotherapy Conference," hosted by the Tianjin Society of Hematology and Regenerative Medicine, was held grandly in the northern coastal city of Tianjin. The conference brought together renowned hematology experts from across the country, focusing on the immunotherapy of hematologic malignancies. They explored the latest advances in the diagnosis and treatment of various hematologic sub-specialties, the pathogenesis of hematologic tumors, and progress in immunotherapy. At the conference, Dr. Bing Xu from The First Affiliated Hospital of Xiamen University delivered an outstanding report titled "Advances in the Diagnosis and Treatment of Intravascular Large B-Cell Lymphoma—Interpretation of the 2023 Chinese Expert Consensus," providing crucial guidance for comprehensively understanding and recognizing this disease. Hematology Frontier invited Dr. Bing Xu to share further insights on this topic.