Posts by Mourabit Halima

The 12th Annual Meeting of the Society of Hematologic Oncology (SOHO 2024) took place in Houston, USA, from September 4 to 7, 2024. It brought together leading experts in hematologic oncology from around the world to discuss the latest research findings and explore new treatment strategies. Among the numerous topics discussed, the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and lymphoblastic lymphoma (T-LBL) was a focal point due to the high relapse rate and treatment complexity associated with these diseases. Traditional treatments often fail to provide long-term remission, and CAR-T cell therapy faces the challenge of inadvertently targeting healthy T-cells, further complicating treatment.

With the rapid advancements in medical technology and deeper insights into the mechanisms of lymphoma, traditional chemotherapy is gradually giving way to a new era of precision-targeted and immunotherapies. Innovative drugs are emerging like bamboo shoots after the rain, offering personalized treatment paths tailored to lymphoma patients. This marks the dawn of a new era in disease management, with the promise of more effective and optimistic treatment outcomes. At the 12th Lu Daopei Hematology Forum, Hematology Frontier invited Dr. Hongmei Jing from Peking University Third Hospital to provide a comprehensive analysis of the current state of lymphoma treatment in China, explore future research directions, and discuss the field's ongoing development.

Graft failure is a rare but fatal complication following haploidentical allogeneic hematopoietic stem cell transplantation. A second transplant is almost the only salvage measure for transplant failure. However, outcomes from second transplants have generally been poor, as reported in previous literature. The 50th European Society for Blood and Marrow Transplantation (EBMT) annual meeting was held in Glasgow, UK, from April 14th to 17th, 2024. The conference focused on the latest advancements in stem cell transplantation and cellular therapy, driving better clinical outcomes for patients with blood disorders. At this conference, a team led by Professor Yuqian Sun from Peking University People's Hospital presented their findings in an oral report titled "Salvage Haploidentical Transplantation with Flu/Cy Regimen and Donor Switching After Primary Graft Failure: Follow-Up Results," which garnered significant attention. Professor Sun was invited to share the main results of this study and the progress in salvage treatments for graft failure after haploidentical allogeneic hematopoietic stem cell transplantation.

From June 13th to 16th, 2024, the 29th Annual Meeting of the European Hematology Association (EHA) was grandly held in Madrid, the capital of Spain. As the largest international conference in the field of hematology in Europe, it attracts experts and scholars from all over the world each year to share and discuss innovative concepts and the latest scientific and clinical research achievements in hematology. At this year's EHA conference, several studies from Professor Xufan Zhu's team at the Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences were selected. This issue highlights two studies on pediatric bone marrow failure diseases (acquired aplastic anemia and Shwachman-Diamond syndrome) and includes insightful commentary from Professor Zhu.

The 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) Congress was held in Bangkok, Thailand, from June 22 to June 26, 2024. As the most influential international event in the field of thrombosis and haemostasis, the ISTH Congress attracts thousands of top experts and scholars from around the world each year, with its profound academic impact and rich academic content. "Oncology Frontier - Hematology Frontier" is dedicated to synchronously delivering cutting-edge academic information. Here, we highlight outstanding research findings to provide academic reference information for the field of hematological diseases.

Aggressive lymphomas progress rapidly and are prone to relapse, with existing treatments still failing to achieve a satisfactory cure rate. Particularly for high-risk patient groups, the demand for precise and efficient treatments is more urgent. The 12th Annual Meeting of the Society for Hematologic Oncology (SOHO 2024) was held in Houston, USA, from September 4th to 7th, 2024, attracting top experts in the field of hematologic malignancies from around the world to exchange the latest research findings and discuss new strategies for treatment. During the conference, "Hematology Frontier" had the honor to interview Dr. Astrid Pavlovsk from the Pavlovsky Center. She provided an in-depth analysis of the efficacy, safety, and current status of new therapies in the treatment of aggressive lymphomas, with a special focus on key issues such as patient individual differences, offering insights for clinical practice.

The 29th European Hematology Association (EHA) Annual Meeting was grandly held in Madrid, Spain, from June 13-16, 2024. As the largest international conference in the field of hematology in Europe, it attracts experts and scholars from around the world every year to share and discuss innovative ideas and the latest scientific and clinical research findings in hematology. At this year's conference, the latest classification standards and clinical research outcomes for MDS received widespread attention. "Oncology Frontier - Hematology Frontier" invited Professor Hongyan Tong from The First Affiliated Hospital, Zhejiang University School of Medicine to provide an in-depth interpretation of the key updates in the latest WHO MDS classification standards and share her team's groundbreaking research achievements in MDS, particularly in the MDS-f subtype.

The 29th Annual Congress of the European Hematology Association (EHA) was grandly held in Madrid, Spain, from June 13 to 16, 2024. As the largest international conference in the field of hematology in Europe, it attracts experts and scholars from all over the world every year to share and discuss innovative ideas and the latest scientific and clinical research findings in hematology. At this year's conference, a study by Dr. Yang Liang from Sun Yat-sen University Cancer Center was selected for poster presentation, exploring how FLT3-ITD promotes immune escape in AML cells by up-regulating CD47 expression and reducing the phagocytic ability of macrophages. To provide insight into these research findings, "Oncology Frontier-Hematology Frontier" invited Dr. Yang Liang to give us a brief introduction to the study.

At the 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) conference, the research team led by Dr. Xiaoyu Zhu and Dr. Aijie Huang from The First Affiliated Hospital of the University of Science and Technology of China (Anhui Provincial Hospital) garnered significant attention. Their study on the efficacy and safety of avatrombopag for treating thrombocytopenia following cord blood transplantation (UCBT) was selected for oral presentation (OC33.3), with Dr. Huang delivering the report. This study not only showcases the exceptional capabilities of Chinese research teams in hematology but also contributes valuable insights to the global hematology community. "Oncology Frontier - Hematology Frontier" had an exclusive interview with Dr. Aijie Huang to delve deeper into the research and discuss future plans in the field of UCBT.