Oriental Insight | Professors Xiaoyun Mao and Wen Xu’s Team Publishes a Comprehensive Review on Engineered Upconversion Nanoparticles for Precision Theranostics in Breast Cancer 

Oriental Insight | Professors Xiaoyun Mao and Wen Xu’s Team Publishes a Comprehensive Review on Engineered Upconversion Nanoparticles for Precision Theranostics in Breast Cancer 

2025.10.21
Breast cancer remains the most common malignancy among women, with persistently high incidence and mortality rates. Its heterogeneity, drug resistance, and the toxicity associated with conventional therapies continue to challenge clinical management.In recent years, rare-earth-doped upconversion nanoparticles (UCNPs) have attracted growing attention in breast cancer research owing to their unique optical properties, tunable synthesis, and flexible functionalization strategies.Recently, the research teams led by Professor Xiaoyun Mao from the First Affiliated Hospital of China Medical University and Professor Wen Xu from the School of Physics and Materials Engineering, Dalian Minzu University, published a cover review in Theranostics titled 'Engineered Upconversion Nanoparticles for Breast Cancer Theranostics.'This review systematically summarizes the progress of UCNP-based strategies in breast cancer diagnosis and therapy, while also discussing challenges in clinical translation and future development directions.
ESMO 2025丨An Academic Feast Awaits — Highlights from the Uro-Oncology Field You Won’t Want to Miss!

ESMO 2025丨An Academic Feast Awaits — Highlights from the Uro-Oncology Field You Won’t Want to Miss!

2025.10.16
At the highly anticipated ESMO Congress, a wealth of cutting-edge advances will be presented, with uro-oncology standing out as one of the most vibrant and fast-evolving fields. This year, 22 Late-Breaking Abstracts (LBAs) will be showcased, accounting for nearly half of all oral presentations (45 in total) within the uro-oncology track — a testament to the field’s dynamic research momentum and strong clinical relevance.Oncology Frontier – Urology Frontier has carefully selected ten key studies and invited leading Chinese experts to share their insights and expectations.
ISEH 2025 | Professor Fumio Arai: Regulatory Mechanisms of Hematopoietic Stem Cell Quiescence and Their Clinical Translation Prospects

ISEH 2025 | Professor Fumio Arai: Regulatory Mechanisms of Hematopoietic Stem Cell Quiescence and Their Clinical Translation Prospects

2025.10.14
The 54th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH 2025) was held from September 24–27, 2025, in Kumamoto, Japan, bringing together leading global experts in hematology to discuss cutting-edge advances in basic hematology, immunology, stem cell research, and cell and gene therapy. One of the major highlights of the event was the Sino-Japanese Joint Symposium on Stem Cells and Cellular Therapy, which drew wide attention. At the symposium, Professor Fumio Arai from Kyushu University, Japan, delivered an insightful presentation titled “Signaling networks governing hematopoietic stem cell quiescence.” In this interview, Oncology Frontier – Hematology Frontier invited Professor Arai to discuss the role of signaling networks in maintaining stem cell function and their potential in clinical applications.
Any level of alcohol can be harmful for MASLD patients

Any level of alcohol can be harmful for MASLD patients

2025.10.12
A recent study by Prof. Wai-Kay Seto (The University of Hong Kong) and Prof. Jie Li (Drum Tower Hospital, Nanjing University Medical School), published in Alimentary Pharmacology & Therapeutics, systematically reviewed the epidemiology, pathogenic mechanisms, and prognostic impact of alcohol use in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), showing that alcohol consumption significantly complicates disease progression and prognosis.