2024 CUDA丨Dr. Zhisong He: China’s Leading Role in Kidney Cancer Surgical Techniques and the National Quality Control Program Enhancing Treatment Standards at the 2024 CUDA Annual Meeting

2024 CUDA丨Dr. Zhisong He: China’s Leading Role in Kidney Cancer Surgical Techniques and the National Quality Control Program Enhancing Treatment Standards at the 2024 CUDA Annual Meeting

Kidney cancer is one of the three most common urological tumors in China, with an increasing incidence rate in recent years. As surgical techniques and new treatment strategies for kidney cancer have advanced, patient survival rates have also improved. At the 2024 Annual Meeting of the Urological Surgeon Branch of the Chinese Medical Doctor Association (CUDA) in Xi'an, Oncology Frontier - Urology NewsUrology Frontier invited Professor He ZhisongDr. Zhisong He from Peking University First Hospital to share insights on the development of kidney cancer surgery in China, second-line treatments for advanced kidney cancer, and progress in the national kidney cancer quality control project.
2024 CUDA丨Dr. Hailong Hu: Exploring Greater Benefits for NMIBC Patients Through Advances in Novel Therapies

2024 CUDA丨Dr. Hailong Hu: Exploring Greater Benefits for NMIBC Patients Through Advances in Novel Therapies

Non-muscle-invasive bladder cancer (NMIBC) accounts for over 70% of all bladder cancer cases. For NMIBC patients, the primary treatment goals are to eliminate tumor cells, prevent recurrence and progression, while preserving bladder function and quality of life as much as possible. From August 8-11, 2024, the Annual Meeting of the Urological Surgeon Branch of the Chinese Medical Doctor Association (CUDA) was held in Xi'an. Following the event, Urology Frontier invited Dr. Hailong Hu from The Second Hospital of Tianjin Medical University to share insights on the unmet clinical needs of NMIBC patients in China, recent advances in novel treatment strategies, and future development directions.
Spotlight on Ideal Target Antigens and Resistance in Antibody-Drug Conjugates: Strategies for Competitive Advancement

Spotlight on Ideal Target Antigens and Resistance in Antibody-Drug Conjugates: Strategies for Competitive Advancement

In the rapidly evolving field of oncology, antibody-drug conjugates (ADCs) have emerged as one of the most promising advancements in targeted cancer therapy. The groundbreaking article titled "Spotlight on Ideal Target Antigens and Resistance in Antibody-Drug Conjugates: Strategies for Competitive Advancement," led by renowned oncologist Academician Binghe Xu, and co-authored by Dr. Mingxia Jiang and Dr. Qiao Li from the Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, delves into the intricate world of ADCs. Published in the esteemed Drug Resistance Updates journal with an impact factor of 15.8, this article not only highlights the transformative potential of ADCs in precision oncology but also addresses the formidable challenge of drug resistance that threatens to undermine their efficacy.
Poly (Adenosine Diphosphate-Ribose) Polymerase Inhibitors: A New Hope in the Fight Against Triple-Negative Breast Cancer

Poly (Adenosine Diphosphate-Ribose) Polymerase Inhibitors: A New Hope in the Fight Against Triple-Negative Breast Cancer

In the rapidly evolving field of oncology, breakthroughs are continuously shaping the way we approach the most challenging cancers. One such breakthrough is the potential of Poly (Adenosine Diphosphate-Ribose) Polymerase inhibitors (PARPi) in the treatment of triple-negative breast cancer (TNBC), a particularly aggressive and hard-to-treat subtype of breast cancer. Academician Binghe Xu from the Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College has authored a study published in Medicinal Research Reviews, a journal with an impact factor of 10.9. The study, titled “Poly (adenosine diphosphate-ribose) polymerase inhibitors in the treatment of triple-negative breast cancer with homologous recombination repair deficiency,” explores the potential of novel therapies known as PARP inhibitors. It specifically examines how these therapies can target the unique vulnerabilities of triple-negative breast cancer tumors with homolo
SIFIC 2024 | Dr. Xiaodong Gao: Integrating Global Expertise to Explore New Strategies for Infection Control in China

SIFIC 2024 | Dr. Xiaodong Gao: Integrating Global Expertise to Explore New Strategies for Infection Control in China

The 20th Shanghai International Forum for Infection Control (SIFIC), in conjunction with the 8th Oriental Forum on Challenging Infectious Diseases (OFCID) and the Academic Corference of Global Chinese Association of Clinical Microbiology & Infectious Diseases , were held at the Shanghai International Convention Center from July 25-27, 2024. At this academic event, Dr. Xiaodong Gao from Zhongshan Hospital  delivered an in-depth lecture on key topics such as hospital infection assessment, infection control management, hand hygiene practices, and the WHO Global Action Plan on Infection Prevention and Control. In an interview with Infectious Diseases Frontier, Dr.  Gao not only reviewed the founding vision of SIFIC but also provided an in-depth analysis of strategies for infection prevention and control (IPC), the details of hand hygiene management, and how multidisciplinary collaboration can strengthen infection control efforts.
AIDS Hot Topic Commentary | Dr. Linghua Li’s Team: Successful Construction of a Chronic SHIV/HBV Co-infection Model in Rhesus Macaques

AIDS Hot Topic Commentary | Dr. Linghua Li’s Team: Successful Construction of a Chronic SHIV/HBV Co-infection Model in Rhesus Macaques

Due to similar transmission routes, approximately 20% of people living with HIV (PLWH) are co-infected with hepatitis B virus (HBV). For decades, rhesus macaques (RMs) have served as a model for HIV research, but they have never been used to study HIV/HBV co-infection. At the AIDS 2024 conference, a research team from Oregon Health & Science University presented an oral report on their successful construction of an RM model co-infected with SHIVDH12 Clone 7 and HBV genotype D. A key advantage of this animal model is the ability to obtain longitudinal biopsies and dynamically monitor changes in immune cell phenotypes and ALT levels, providing better insights into the pathogenesis of co-infection. This article invites Dr. Linghua Li’s team from Guangzhou Eighth People's Hospital, Guangzhou Medical University to delve into this study and interpret the deeper significance behind these research findings.
Dr. Jidong Jia: China’s New Guidelines for Chronic Hepatitis B Mark a Transition from Following to Leading

Dr. Jidong Jia: China’s New Guidelines for Chronic Hepatitis B Mark a Transition from Following to Leading

From July 25 to 28, 2024, the Combined GIHep & SHC 2024 was held in Singapore. Dr. Jidong Jia from Beijing Friendship Hospital, Capital Medical University, participated in the Chronic Hepatitis B symposium and delivered a remarkable presentation on the new Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2022 Edition) (hereinafter referred to as the "New Guidelines"). Hepatology Digest conducted an exclusive interview with Professor Jia to discuss the highlights of his presentation.
AIDS Interview丨Inhibiting HIV Transcription to Achieve Maximum Disease Remission

AIDS Interview丨Inhibiting HIV Transcription to Achieve Maximum Disease Remission

At the AIDS 2024 conference, Dr. Melanie Ott from the University of California, San Francisco, delivered a special report titled "The Sound of Silence: Tackling HIV Transcription to Achieve Remission," which garnered widespread attention. Following the conference, Infectious Diseases Frontier conducted an in-depth interview with Dr.  Ott, where she elaborated on the significance of HIV transcription mechanisms in regulating viral reservoirs, which play a crucial role in the rebound of the virus after treatment interruption. Professor Ott highlighted that a novel strategy involving the use of transcription inhibitors in combination with existing antiretroviral therapy (ART) could potentially suppress transcriptional activity in reservoir cells, thereby delaying viral rebound and reducing immune activation, bringing new hope and breakthroughs to the field of HIV treatment.
Dr. Yingli He: Building a Defense Against Liver Cancer—Antiviral Treatment Strategies for CHB Patients in the Context of Comprehensive Liver Cancer

Dr. Yingli He: Building a Defense Against Liver Cancer—Antiviral Treatment Strategies for CHB Patients in the Context of Comprehensive Liver Cancer

Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) presents a significant public health challenge in China, with the majority of HCC patients being diagnosed at an advanced stage. Postoperative survival rates for HBV-related HCC patients are often poor. Therefore, the prevention and treatment of HBV-related HCC urgently require comprehensive management. China has achieved remarkable success in primary prevention of hepatitis B. Regular screening and early treatment in high-risk populations are crucial to reducing HCC mortality. Antiviral treatment is an important measure for secondary and tertiary prevention of HBV-related HCC. At the 2024 World Hepatitis Day and the Elimination of Hepatitis Harm Action Conference, Dr. Yingli He from the First Affiliated Hospital of Xi'an Jiaotong University shared insights into antiviral treatment strategies for chronic hepatitis B (CHB) patients from the perspective of comprehensive liver cancer management.
How Should Chinese Women Approach Breast Cancer Screening?

How Should Chinese Women Approach Breast Cancer Screening?

Breast cancer has now become the most common malignant tumor worldwide and is one of the most prevalent cancers among Chinese women, posing a serious threat to their physical and mental health. While significant progress has been made in the treatment and drug development for breast cancer, providing more targeted treatment options for different types of patients and improving survival rates and quality of life, our ultimate goal is to reduce the incidence of breast cancer through screening and prevention. Early detection is crucial for improving treatment outcomes and extending survival times. This article discusses breast cancer screening and how high-risk groups can reduce their risk of developing breast cancer.