Dr. Wei Yu: Research Progress in ASCO-GU 2023 Urothelial Carcinoma

Dr. Wei Yu: Research Progress in ASCO-GU 2023 Urothelial Carcinoma

The American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium 2023 (ASCO-GU 2023) kicked off on February 16th in San Francisco, USA. In the field of urothelial carcinoma (UC), significant progress has been made in research. Immunotherapy with immune checkpoint inhibitors (ICIs) in the first-line treatment for advanced UC, as reported in the final analysis of the IMvigor130 study, has provided more information on the population benefiting from immune therapy. Additionally, immunotherapy has expanded into early-stage treatment, with the updated 3-year follow-up data from the CheckMate 274 study showing a Disease-Free Survival (DFS) of up to 52.6 months in the PD-L1 > 1% subgroup. Furthermore, different targets such as Trop-2 and Nectin-4 in antibody-drug conjugates (ADCs) are being explored in various treatment modalities and are extending from later-line to first-line treatment.
Urinary Tumor DNA for MRD Detection in NMIBC rTURBT

Urinary Tumor DNA for MRD Detection in NMIBC rTURBT

The American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO-GU 2023) kicked off in San Francisco on February 16, 2023. On the second day of the conference, during a special session on urothelial carcinoma, Professor Kyle M. Rose from the H. Lee Moffitt Cancer Center presented a prospective study on using cfDNA/utDNA for MRD detection in NMIBC patients undergoing repeat-transurethral resection of bladder tumor (rTURBT).
Dr Zhu Yao’s Team: Significant Survival Differences in Newly Diagnosed mPC Patients between Asian and Caucasian patients, International Clinical Trial Designs Should Consider This Factor

Dr Zhu Yao’s Team: Significant Survival Differences in Newly Diagnosed mPC Patients between Asian and Caucasian patients, International Clinical Trial Designs Should Consider This Factor

Are there differences in long-term prognosis between Asian and Caucasian patients with new metastatic prostate cancer (mPC)? A study presented at the 2023 American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO-GU 2023) by Dr. Zhu Yao's team suggests that among patients receiving different treatment regimens, Asian males have superior overall survival (OS) and cancer-specific survival (CSS) compared to white males in this category. This research highlights the importance of considering Asians as an independent prognostic factor when evaluating individual patient outcomes and the need to include an adequate representation of Asian patients in the design of global multicenter clinical trials.
Comprehensive Research from West China Hospital of Sichuan University

Comprehensive Research from West China Hospital of Sichuan University

The American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium (ASCO-GU 2023) was held in San Francisco, USA, from February 16th to 18th, 2023. Dr. Qiang Wei and Dr. Hao Zeng's team had multiple findings selected for academic exchange at this ASCO-GU symposium. Their work addressed prostate cancer, urinary tract carcinoma, and kidney cancer, covering prospective clinical trials, retrospective studies, and translational research. They shared and conveyed the "West China Experience" and "West China Plan" on the international stage.
Dr. Bo Dai: Research Progress in ASCO-GU 2023 prostate cancer

Dr. Bo Dai: Research Progress in ASCO-GU 2023 prostate cancer

The American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium for 2023 (ASCO-GU 2023) kicked off on February 16th in San Francisco, USA. Numerous innovative treatment studies have emerged in the fields of metastatic hormone-sensitive prostate cancer (mHSPC), metastatic castration-resistant prostate cancer (mCRPC), non-metastatic castration-resistant prostate cancer (nmCRPC), and early/localized prostate cancer. These studies encompass a wide range of therapies, including androgen deprivation therapy (ADT), novel hormonal therapy (NHT), PARP inhibitors (PARPi), immunotherapy, nuclear medicine therapy, and localized treatments.