-

Strategy for Intensification: Efficacy and Safety of BCG Plus ICI in BCG-Naive High-Risk NMIBC Based on 2,590 Patients
During the 2026 European Association of Urology (EAU) Congress, Prof. Saad M.A. from the Department of Medical Oncology at the Mohammed V Military Teaching Hospital, Rabat, Morocco, presented a systematic review and reconstructed Individual Patient Data (IPD) meta-analysis. The study evaluated the clinical value of Bacillus Calmette-Guérin (BCG) combined with Immune Checkpoint Inhibitors (ICIs) in…
-

Shifting Paradigms in MIBC Diagnosis: How Multimodal Imaging Staging Optimizes Clinical Decision-Making
During the recent academic session, Professor Antoine Van Der Heijden from Radboud University Medical Center (Nijmegen, NL) shared comprehensive insights into the management of Muscle-Invasive Bladder Cancer (MIBC). The presentation focused on the clinical significance of histological subtypes, the inherent limitations of traditional Transurethral Resection of Bladder Tumor (TURBT), and the emerging value of MRI…
-

80% CR Rate! SIM0237 Demonstrates Potent Anti-tumor Activity and Favorable Tolerability in BCG-unresponsive High-risk NMIBC
During a recent academic session, Professor Dingwei Ye (Prof. Dingwei Ye) from Fudan University Shanghai Cancer Center provided an in-depth interpretation of the Phase 1/2 clinical study data for SIM0237—an anti-PD-L1/IL-15 variant fusion protein—specifically in patients with Bacillus Calmette-Guérin (BCG)-unresponsive high-risk non-muscle-invasive bladder cancer (NMIBC).
-

52.8% ORR and 87.3% 9-Month PFS Rate: Fruquintinib plus Serplulimab Shows Remarkable Promise in 1st-Line nccRCC
During the recent ASCO GU 2025 (Genitourinary Cancers Symposium), Professor Jiwei Huang from Renji Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine (on behalf of the research team led by Ding Yingjie), presented the updated efficacy and safety data from a multicenter, single-arm, Phase II trial. The study evaluates the combination of Fruquintinib…
-

A Predictive Model for BCG-Unresponsiveness and Progression Based on Five Clinical Factors: A Study of 2,211 Patients
During a recent session on urological oncology, Professor A. Ślusarczyk from the Department of General, Oncological, and Functional Urology at the Medical University of Warsaw, Poland, presented the results of an international multicenter retrospective study. The study aimed to develop and validate a clinical predictive model to identify patients with high-grade non-muscle-invasive bladder cancer (NMIBC)…
-

Real-World Insights into the Safety of First-Line mRCC Combinations: ARON-1 Study Suggests Severe AEs May Predict Superior Survival Benefits
Dr. Biagio Antonio Maiorano from the Department of Medical Oncology, IRCCS San Raffaele Hospital (Milan, Italy), presented a sub-analysis of the ARON-1 study. This analysis evaluated the real-world incidence of grade 3–4 adverse events (AEs) and their clinical impact on overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) receiving first-line immune checkpoint…
-

36% Reduction in DFS Risk: POTOMAC Study Validates Immuno-Combination Therapy for Elderly Patients with High-Risk NMIBC
At a recent academic symposium, Professor Joan Palou from the Department of Urology, Universitat Autònoma de Barcelona, Spain, presented the latest subgroup analysis from the POTOMAC study. The presentation focused on the efficacy and safety of one year of durvalumab (D) in combination with Bacillus Calmette-Guérin (BCG) induction and maintenance therapy for BCG-naïve, high-risk non-muscle-invasive…
-

A Predictive Model for BCG-Unresponsiveness and Progression Based on Five Clinical Factors: A Study of 2,211 Patients
During a recent session on urological oncology, Professor A. Ślusarczyk from the Department of General, Oncological, and Functional Urology at the Medical University of Warsaw, Poland, presented the results of an international multicenter retrospective study. The study aimed to develop and validate a clinical predictive model to identify patients with high-grade non-muscle-invasive bladder cancer (NMIBC)…