IOncology

As the year draws to a close, reflection and progress take center stage. The "2024 Beijing Forbidden City Annual Lung Cancer Conference and the 16th Multidisciplinary Seminar on Advances in Lung Cancer Diagnosis and Treatment," jointly organized by the Beijing Tumor Prevention and Research Association, the China Association of Senior Healthcare, the Beijing Medical Love Public Welfare Foundation, and the Beijing Chen Jumei Public Welfare Foundation, was successfully held on December 13–14, 2024, in Beijing.

Dr. Ming Zhao shares key insights on combining local and systemic therapies to improve liver cancer treatment outcomes. Learn how innovative approaches like immunotherapy and targeted treatments are transforming patient care.

The 2024 Yixian Breast Cancer Conference and the 2nd China Young Breast Cancer Consensus Conference, held on December 27–28 in Guangzhou, brought together leading experts in breast disease to discuss the latest advancements in treatment and management. The conference also focused on consensus guidelines for diagnosing and treating young breast cancer patients, aiming to improve cure rates and rehabilitation outcomes. At the event, Dr. Rui Xu from the Breast Specialty Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine shared cutting-edge findings in breast cancer surgery, offering new perspectives for treatment. In an interview with Oncology Frontier, Professor Xu provided an overview of the latest surgical advancements and developments in integrative medicine for breast cancer.

In 2024, Professor Wu Yilong a luminary in the field of lung cancer and a cornerstone of Oncology Frontier, exemplified unwavering commitment to advancing medical care and education. from leading…

In recent years, breakthroughs in basic research and clinical trials, particularly in combined targeted and immunotherapy strategies and the development of domestically produced novel drugs, have significantly advanced clinical practices in uro-oncology. However, transforming cutting-edge research into practical clinical applications and sharing Chinese expertise with international patients remains an ongoing challenge. The 14th Shanghai Genitourinary Oncology Academic Conference and Annual Meeting of Chinese Anti-Cancer Association—Genitourinary Oncology Committee (CACA-GO) were held in Shanghai from December 6 to 8. Following the event, Urology Frontier invited Professor Dingwei Ye, the conference chair and leading expert from Fudan University Shanghai Cancer Center, to share the highlights and experiences of this impactful event.

In the treatment landscape of HR+/HER2- metastatic breast cancer (MBC), CDK4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) have become a widely used first-line treatment. However, patients with symptomatic visceral metastases often opt for chemotherapy (CT). While some prospective studies suggest that CDK4/6i + ET may yield better outcomes even in patients with visceral metastases, no studies have explored these strategies in real-world settings.

The 47th San Antonio Breast Cancer Symposium (SABCS) is in full swing in San Antonio, USA, showcasing cutting-edge research from around the world. On December 12 (Central Time), during the “Poster Spotlight – Session 8: Novel HER2 Therapeutics”, Dr. Biyun Wang and her team from Fudan University Shanghai Cancer Center presented their groundbreaking findings on GQ1005, a highly promising HER2 antibody-drug conjugate (ADC). The study’s evaluation of GQ1005’s efficacy and safety in HER2-positive metastatic breast cancer (MBC) patients drew significant attention, leading to vibrant discussions among experts. Dr. Wang provides an in-depth interpretation of this important research.

The treatment of HER2-positive breast cancer remains a focal point in clinical research. At the 2024 San Antonio Breast Cancer Symposium (SABCS), a phase 1b study led by Dr. Biyun Wang from Fudan University Shanghai Cancer Center presented promising results (Abstract No. P5-05-02). This study explored the pharmacokinetics and preliminary efficacy of a novel HER2 antibody-drug conjugate (ADC), GQ1001, combined with pyrotinib in patients with HER2-positive metastatic breast cancer (MBC) who had undergone prior treatments. Here, we provide an overview of this groundbreaking research.

At the 2024 San Antonio Breast Cancer Symposium (SABCS), one of the world’s most prestigious events in breast cancer research, Chinese scholars once again demonstrated their exceptional expertise and innovative spirit in the field of breast cancer treatment. A groundbreaking study led by Dr. Nanlin Li and his team from Xijing Hospital of the Air Force Medical University brings renewed hope to breast cancer patients in China and offers fresh strategies to the global breast cancer research community. This study focuses on precision therapy for breast cancer, exploring the efficacy and safety of envafolimab combined with pyrotinib and nab-paclitaxel in the neoadjuvant treatment of HER2-positive breast cancer. Below, we provide a detailed introduction to the research.

From December 10 to 13, 2024, the 47th San Antonio Breast Cancer Symposium (SABCS) took place in San Antonio, USA. As one of the largest and most prestigious scientific gatherings in the field of breast cancer research, SABCS showcased the latest findings, clinical practices, treatment advancements, and technological innovations from the past year.Among the many noteworthy contributions, a study by Dr. Yunjian Liu's team from The Fourth Hospital of Hebei Medical University stood out. Their research focused on the prognostic value of ctDNA monitoring in breast cancer patients undergoing neoadjuvant therapy and was presented as a poster (Abstract No. P3-05-22). The study highlights how personalized ctDNA testing can dynamically monitor minimal residual disease (MRD), predict treatment efficacy and recurrence risk, and provide valuable insights for clinical decision-making. Oncology Frontier interviewed Professor Liu onsite for an in-depth discussion.