Hematology Frontier

Acute promyelocytic leukemia (APL) is a highly aggressive blood disorder, and its treatment has always been a challenge in the field of hematology. Chinese scholars have contributed the arsenic trioxide (ATO) regimen for global APL patients. Since the APL0406 study reported in the New England Journal of Medicine in 2013, all-trans retinoic acid (ATRA) combined with ATO has replaced ATRA combined with chemotherapy as the standard treatment for patients with intermediate and low-risk APL. However, whether this regimen is suitable for high-risk APL patients is still lacking in randomized controlled trial reports. At the 29th Annual Congress of the European Hematology Association (EHA 2024) held from June 13 to 16, 2024, Professor Uwe Platzbecker from Leipzig University in Germany presented the key results of the APOLLO study in an oral report. The study showed that the combination of ATO and ATRA provides a new treatment strategy for high-risk APL patients, offering valuable insights into the current state of APL treatment and guiding future research directions and clinical practices. "Oncology Frontier-Hematology Frontier" specially invited Professor Platzbecker on-site to share the important findings and clinical significance of the APOLLO study.

The 29th European Hematology Association (EHA) Annual Congress was held in Madrid, Spain, from June 13 to 16, 2024. As the largest international conference in the field of hematology in Europe, it attracts experts and scholars worldwide to share and discuss innovative ideas and the latest scientific and clinical research achievements in hematology. At this year's EHA Congress, three studies from Professor Sanbin Wang's team at The 920th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army were selected as posters (abstracts P544, 965, and 420), exploring treatment advancements in AML, RRMM, and r/r B-ALL, respectively. Oncology Frontier-Hematology Frontier invited Professor Sanbin Wang to share and interpret the content and significance of these studies.

The 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) Congress was held in Bangkok, Thailand, from June 22 to June 26, 2024. As the most influential event in the field of thrombosis and hemostasis, the ISTH Congress attracts thousands of top experts and scholars from around the world with its profound academic impact and rich content. During this prestigious event, Oncology Frontier-Hematology Frontier had the honor of interviewing Academician Heyu Ni from the Canadian Academy of Health Sciences, who also served as the Chair of the Joint ISTH Congress and Global Chinese Thrombosis and Hemostasis Conference. In this interview, Academician Ni shared his extensive academic experience and unique insights, providing us with valuable academic reflections and perspectives. We have organized this interview into an article for our readers.

The 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) Congress was held in Bangkok, Thailand, from June 22 to June 26, 2024. As the most influential event in the field of thrombosis and hemostasis, the ISTH Congress attracts thousands of top experts and scholars worldwide with its profound academic impact and rich content. The "ISTH China's Voices" column of Oncology Frontier-Hematology Frontier aims to showcase outstanding research achievements from the Chinese academic community at ISTH. In this issue, we present a research finding from Dr. Enhao Li of Professor Xuefeng Wang's team at Ruijin Hospital, Shanghai Jiaotong University School of Medicine. Dr. Li's oral presentation at ISTH delved into the differential immune responses to FVIII and FIX in hemophilia A (HA) and hemophilia B (HB) patients, providing valuable academic insights for the hematology field.

The 32nd International Society on Thrombosis and Haemostasis (ISTH 2024) Congress was held in Bangkok, Thailand, from June 22 to June 26, 2024. As the most influential event in the field of thrombosis and hemostasis, the ISTH Congress attracts thousands of top experts and scholars from around the world with its profound academic impact and rich content. During this prestigious event, Oncology Frontier-Hematology Frontier had the honor of interviewing Academician Heyu Ni from the Canadian Academy of Health Sciences, who also served as the Chair of the Joint ISTH Congress and Global Chinese Thrombosis and Hemostasis Conference. In this interview, Academician Ni shared his extensive academic experience and unique insights, providing us with valuable academic reflections and perspectives. We have organized this interview into an article for our readers.

Circulating tumor DNA (ctDNA) testing allows for continuous dynamic monitoring of tumor genetic variations without relying on tissue samples. This liquid biopsy technology has been widely used in clinical breast cancer research for prognosis and treatment evaluation, but there are still no standards for ctDNA testing, including population selection, testing frequency, and testing methods. At the recent 5th Comprehensive Cancer Treatment Academic Conference of the Dalian Xinghai Medical Forum, Oncology Frontier invited Professor Pengfei Qiu from Shandong Cancer Hospital, and Professor Hao Wang fro

At the recently held 29th Annual Congress of the European Hematology Association (EHA), Professor John Gribben, former chairman of EHA and head of the Hematological Center at Barts Cancer Institute, Queen Mary University of London, was awarded the José Carreras Prize for his outstanding contributions in the field of immunology research. "Oncology Frontier-Hematology Frontier" specially invited Professor John Gribben to share his research findings and his feelings about the award. In addition, Professor John Gribben also discussed the significance of patient-centered treatment in the field of hematology and emphasized the importance of global cooperation and inclusive clinical trials to advance the field and provide the best care for patients worldwide.

Acute Lymphoblastic Leukemia (ALL), as an aggressive form of blood cancer, poses a serious threat to patients' lives. Despite significant progress in treatment in recent years, drug resistance remains a major obstacle to improving patient survival rates and quality of life. At the recently held 29th Annual Congress of the European Hematology Association (EHA 2024), the research findings of Professor Jean-Pierre Bourquin from the Universitätsspital Zürich, Zürich, Switzerland , were particularly significant. The research has not only made important contributions to understanding the complex biological mechanisms of ALL but also achieved breakthrough progress in the study of drug resistance. "Oncology Frontier - Hematology Frontier" specially invited Professor Bourquin to share the core theme of precision hematology and his key findings in the research of ALL drug resistance at the venue.

The 29th Annual Congress of the European Hematology Association (EHA) was held in Madrid, Spain, from June 13 to 16, 2024. This conference is the largest international event in the field of European hematology, attracting numerous internationally renowned experts and scholars every year to share and discuss innovative ideas, the latest scientific research, and clinical research results in the field of hematology. At this conference, "Oncology Frontier - Hematology Frontier" specially invited Professor Antonio Almeida, the Chairman of the EHA Conference and the founding dean of the Hospital da Luz and Católica Medical School in Lisbon, Portugal, Lisbon, Portugal, to discuss the main highlights and important progress of the conference, covering a range of topics including breakthrough research, international cooperation, and the future challenges in the field of hematology.